Artificial intelligence is transforming healthcare faster than many imagined. From detecting disease earlier and personalising treatment to easing pressure on overstretched health systems, AI is already changing the way care is delivered. But technology alone isn't enough. Real progress depends on trust, responsible governance, and ensuring that innovation puts patients, not algorithms, at the heart of healthcare.

In this episode, Hans Martens, Senior Counsel at Incisive Health, speaks with Dr. Ricardo Baptista Leite, former Member of the Portuguese Parliament and Chief Executive Officer of Health AI – The Global Agency for Responsible AI in Health. Drawing on his experience at the intersection of policymaking, global health, and responsible AI, Dr. Leite explains how governments and health systems can harness AI safely, ethically, and effectively.

Together, they explore how AI could transform everything from prevention and early diagnosis to healthcare delivery and health system resilience. They also discuss the governance, regulation, and public trust needed to ensure AI empowers healthcare professionals, improves patient outcomes, and makes care more, not less, human.

This is Break the Bubble. In this episode:"The AI Doctor Will See You Now".

Across Europe, a new chapter in Health Technology Assessment is taking shape.

Member States are now working together to assess the clinical value of new medicines through Joint Clinical Assessments under the EU HTA Regulation.

One year into its application, the conversation is moving from theory to reality. What does implementation actually look like? How are the first Joint Clinical Assessments being carried out? And why does this matter for patients, health systems and Europe’s innovation environment?

In this episode of Break the Bubble, Incisive Health Senior Counsel Hans Martens sits down with Maya Matthews, Head of the HTA Unit at DG SANTE.

Together, they explore how the first phase of the Regulation is taking shape, starting with oncology medicines and gene therapies. They discuss how Joint Clinical Assessments are aligned with EMA marketing authorizations, how patients and clinicians are now involved in shaping the assessment process, and how cooperation at EU level aims to reduce duplication while increasing transparency and quality.

What could this mean for innovation, for trust in decision-making and for access to new medicines across Europe?

Across Europe, health systems are at a critical turning point. Ageing populations, workforce shortages

and rising care needs are testing the sustainability of our model and deepening inequalities across

Europe. The question is no longer whether change is needed, but how quickly and how efficiently we

act.

In this episode of Break the Bubble, Incisive Health Senior Counsel, Hans Martins sits down with, Jan De

Maeseneer, a leading voice in primary health care, former chair of the DG SANTE Expert Panel on

effective ways of investing in health, he now heads the WHO Collaborating Centre for Family Medicine

and Primary Health Care at Ghent University.

Together they explore what it will take to move from reactive sick care towards more resilient, person-

centred health systems.

They discuss why strengthening primary and community care matters, how prevention and population-

based approaches can ease pressure on health systems, and what can be done to reduce widening

health inequalities. What happens if we fail to act, and what opportunities open up if we get this

transformation right?