Most women are following biohacking advice that was never designed for their biology, and the results speak for themselves: exhaustion, weight that will not move, accelerated aging, and a growing sense that the body is working against them no matter what they try.

In this episode of The Whole and Complete Woman Podcast, originally recorded live at the All Things Woman Summit, Dr. Alicia Newsome presents a session from Natosha Ash, M.S., a scientist in human genetics and genomics who specializes in nutrigenetics and biological aging. Natosha has dedicated her work to making the science of aging understandable and actionable for women, because aging is not just about the number of years lived. It is about how the body is functioning at the cellular level, and those two things are not always the same.

This session goes deep on the difference between chronological and biological aging and why it matters, Natosha's five-level framework for understanding how the body ages from the inside out, starting with circadian disruption, moving through mitochondrial energy, chronic inflammation, and cellular cleanup, and ending with structural changes that eventually show up visibly, the unique aging accelerators women face because of hormonal transitions, mitochondrial function, the gut-hormone relationship, sleep, nutrition, and genetics that all intersect throughout a woman's lifespan, why women can follow the exact same diet, exercise program, and supplement routine and have completely different results, and how genetics and nutrigenomics give us another layer of information for creating individualized strategies rather than assuming one universal approach applies to everyone. If you have ever felt like you are doing everything right and still not seeing the results you expected, this session will give you the real explanation and a place to start.

Chapters: 00:00 - Welcome and Introduction 02:53 - Chronological Age vs. Biological Age and Why the Difference Matters 04:01 - How Biological Age Is Measured and What It Tells You 11:28 - Why Women's Aging Deserves Its Own Conversation 14:19 - Level One: Circadian Disruption and Why Everything Starts Here 20:34 - How to Align Your Circadian Biology from Foundation to Advanced 25:13 - Intermittent Fasting, Longevity Genes, and Why It Has to Be Tailored to You 26:00 - Genetic Keys for Level One: Chronotype, Hunger, and Exercise Response 30:16 - Level Two: Energy Collapse and the NAD Drop That Starts at 25 33:02 - Sirtuins, Longevity Genes, and Estrogen as Your Mitochondrial Manager 38:26 - How to Activate PGC-1 Alpha Without Estrogen 39:12 - Genetic Keys for Level Two: How Your Genes Determine Your NAD Response 43:28 - Level Three: When Inflammation Gets Locked On

Connect with Natosha Ash, M.S.:

Instagram: @Natural_Natosha Linktree: https://linktr.ee/natural_natosha

ALL THINGS WOMAN SUMMIT: This session was originally recorded live at the All Things Woman Summit. If you would like to attend the next summit or apply to be considered as a speaker, visit www.allthingswomensummit.com.

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INVITE DR. ALICIA TO SPEAK: https://www.dralicianewsome.com/invite-to-speak/

SEE DR. ALICIA NEWSOME ON TV: https://youtube.com/watch?feature=shared&v=uMUmgzkSeMU

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Keywords: biological age, biohacking, genetics, longevity, circadian rhythm, mitochondria, NAD, women's health, functional medicine, nutrigenetics, nutrigenomics, aging, perimenopause, menopause, inflammation, gut-hormone connection, personalized health, Natosha Ash, All Things Woman Summit, The Whole and Complete Woman Podcast.