『BIOACTIVE』のカバーアート

BIOACTIVE

BIOACTIVE

著者： Riley D. Kirk Ph.D.
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Dr. Riley Kirk is a cannabis research scientist and educator. She obtained her Ph.D. in pharmaceutical sciences, specializing in natural product chemistry, studying the traditional and contemporary uses of hundreds of medicinal plants. She is currently an assistant associate professor at the University of Rhode Island, has worked as an immunology scientist in the biotech industry, and works in the cannabis industry studying the chemical complexity of cannabis smoke. Riley is also the co-founder of the cannabis research and education non-profit organization called the Network of Applied Pharmacognosy (NAP). Through NAP and on her podcast, Riley uses science as advocacy to research and communicate findings that highlight the unique power of natural products. The goal of Riley’s work is to unite people in the Cannabis industry, academia, and consumers to further the reach of Cannabis education and reduce harm. Riley is passionate about making Cannabis science accessible through social media channels and alternative media which lead to Bioactive; an educational podcast which disseminates the chemistry and pharmacology of natural products. On this bi-weekly podcast, she covers current news and research surrounding cannabis, psychedelics, toxins, pharmaceuticals & other bioactive substances. Listen for special guests highlighting community stories.881375 生物科学 科学
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  • The Gut-Brain Axis with Dr. Rick Pescatore

    The Gut-Brain Axis with Dr. Rick Pescatore
    2026/08/25
    In this episode of the Bioactive Podcast, Dr. Riley Kirk sits down with Dr. Rick Pescatore, board-certified emergency physician, Editor-in-Chief of Emergency Medicine News, and founder of BellyMD, for a fascinating deep dive into the gut-brain connection and what it means for cannabis users and patients dealing with unexplained digestive symptoms. Dr. Pescatore explains how the gut and brain communicate through the vagus nerve, why the gut has been called the “second brain,” and how genetics, diet, gut bacteria, inflammation, and cannabis can all influence this complex system. The conversation also explores cannabinoid hyperemesis syndrome (CHS) and why understanding CHS requires looking beyond cannabis alone and considering the broader gut-brain system. We also get into GLP-1 medications and gut-brain medicine, nausea and vomiting, microbiome health, micronutrient deficiencies, vitamin B1 (thiamine), magnesium, and whether personalized health data could help us better understand why someone feels unwell. Dr. Pescatore shares how emerging tools, including phenomic data, wearable technology, AI, and the Menome platform, could help patients identify patterns that traditional medicine may overlook. We also discuss cannabis and the gut microbiome, CHS, thiamine deficiency, antibiotics and gut health, personalized medicine, patient autonomy, and the future of gut-brain healthcare. In this episode, we explore: - What is the gut-brain axis and how does the gut communicate with the brain? - Why does the gut have such a major role in neurotransmitters and brain health? - What does the gut microbiome have to do with anxiety, depression, and other conditions? - What is cannabinoid hyperemesis syndrome (CHS), and how does it fit into gut-brain health? - Could underlying gut-brain dysfunction contribute to cannabis-related symptoms? - How do GLP-1 medications affect the gut-brain axis? - What role do vitamin B1, magnesium, and micronutrients play in gut-brain health? - Can microbiome testing and wearable data help personalize healthcare? - Could AI help patients better understand their own health? - What does the future of personalized gut-brain medicine look like? This is a conversation about cannabis, medicine, the microbiome, nutrition, neuroscience, personalized health, and the emerging science connecting them all. CHAPTERS: 00:00 CHS Big Picture 01:17 Podcast Welcome 02:18 Meet Dr Pescatore 03:50 Defining Gut Brain Axis 05:50 Second Brain Neurons 06:42 Leaky Gut Explained 07:44 Omics And AI Boom 11:18 GLP1s As Gut Brain Drugs 13:57 GLP1 Risks And Nausea 16:46 Supplements And Diet Basics 18:28 Personalized Testing Options 19:57 Menome Phenomic App 23:46 Digital Biomarker Score 24:56 CHS Telemedicine Pipeline 27:32 Scromiting Dopamine Clue 28:28 What Really Causes CHS 29:14 Dopamine Targeted Treatment 30:06 Genetics And Dopamine Links 31:49 Gut Inflammation Hypersensitivity 32:52 Microbiome And Vitamin Deficits 34:29 Probiotics Versus Supplements 35:54 Thiamine Magnesium Protocol 37:33 Side Effects And Vivid Dreams 40:33 Can Patients Use Again 41:48 FMT And Antibiotic Fallout 43:44 Cannabis Heart Risk Reality 45:34 ER Priorities Psychosis CHS 46:25 Prevention Tips And B1 For All 47:25 Social Media And The App 50:10 Patient Autonomy And Wrap Up Explore Dr. Rick Pescatore & BellyMD 🌐 Rick Pescatore: rickpescatore.com 🌐 BellyMD: belly-md.com 📱 Menome: menome.belly-md.com Bioactive Podcast listeners can get 3 months of free access to Menome with code MGBSUB1MO. 🌿 MGB+ Calm: BellyMD MGB+ Calm Use code RILEY15 for discount. Want Exclusive Content and ad-free episodes? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Sign Up for Emails! www.AppliedPharmacognosy.org Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Disclaimer: This episode is for educational and informational purposes and is not a substitute for individualized medical advice. Learn more about your ad choices. Visit megaphone.fm/adchoices
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    53 分
  • What went down at the Cannabis Rescheduling Hearing with Max Jackson

    What went down at the Cannabis Rescheduling Hearing with Max Jackson
    2026/08/07
    What actually happened inside the DEA’s cannabis rescheduling hearing? In this timely episode of the Bioactive Podcast, Dr. Riley Kirk sits down with Max Jackson, former commercial cannabis cultivator and founder of Cannabis Wise Guys, to unpack what he witnessed firsthand at the DEA hearing on moving cannabis from Schedule I to Schedule III. Max spent most of the hearing inside the room, taking handwritten notes because recording and livestreaming were not permitted. As someone who previously managed a commercial cultivation facility with approximately 13,000 flowering cannabis plants, he offers a unique perspective on the arguments being made about cannabis, medical use, public health, research, and the plant itself. Together, Riley and Max break down who opposed rescheduling, what the government and opposing parties argued, and some of the surprising claims and misconceptions that came up during the proceedings. They discuss the difference between whole-plant cannabis and isolated cannabinoids, the challenges of dosing and medical education, cannabis research limitations, adverse effects, and why the lack of cannabis research is itself connected to decades of Schedule I restrictions. The conversation also explores what rescheduling to Schedule III could actually mean, what happens next in the process, why the administrative judge does not make the final decision, and why the DEA ultimately holds that decision. Whether you're a cannabis consumer, home grower, medical professional, researcher, cultivator, cannabis business owner, or simply trying to understand the future of cannabis policy in the United States, this episode gives you an inside look at a hearing most people never had the opportunity to see. CHAPTERS: 00:00 Welcome and Guest Intro 00:40 Max Jackson Background 01:36 Why He Attended Hearing 02:52 Security and Closed Doors 06:46 Who Opposed Rescheduling 08:18 Bias and Expert Framing 10:58 Psychosis and CUD Claims 17:08 IV THC and Syringe Confusion 19:16 Plant vs Single Molecule 23:36 No Medical Use Argument 26:45 Youth Access and Regulation 31:13 Humboldt Crime Fears 33:07 Hearing Strategy Angle 33:57 Drugged Driving Testing 35:50 Tolerance And Impairment 38:30 Research Collaboration Gaps 41:10 Breastfeeding And Postpartum 42:54 ER Harms And Education 45:48 Schedule Logic Debate 51:21 DEA Museum Narrative 54:26 Van Check At DEA 57:49 What Happens Next 59:27 Wrap Up And Resources Connect with Max Jackson Cannabis Wise Guys https://cannabiswiseguys.com/ Cannabis Fact Book https://thecannabisfactbook.com/ Email: max@cannabiswiseguys.com IG: www.instagram.com/cannabiswiseguys/ Want Exclusive Content and ad-free episodes? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Sign Up for Emails! www.AppliedPharmacognosy.org Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 時間 4 分
  • Should THC Be a Range Instead of One Number? with guest Ben Cleary

    Should THC Be a Range Instead of One Number? with guest Ben Cleary
    2026/07/30
    In this episode of the Bioactive Podcast, Dr. Riley Kirk sits down with cannabis research scientist Ben Cleary to unpack groundbreaking research published in Scientific Reports examining THC variability in cannabis flower and what it means for consumers, cultivators, laboratories, and regulators. If you've ever wondered why the same strain can feel different from batch to batch—or why chasing the highest THC percentage often leads to disappointment—this conversation explains the science behind it. Ben shares how his team's research demonstrates the natural variability of THC within a single cannabis plant and why reporting one THC percentage may not accurately represent what consumers actually purchase. Together, Riley and Ben discuss the future of cannabis labeling, range-based THC reporting, lab testing variability, terpene science, chemical diversity, and how better education can improve purchasing decisions and consumer trust. They also explore why aroma may be a better guide than THC percentage alone, how Canada's cannabis industry is beginning to implement THC ranges, the role of laboratory variation in cannabis testing, and what future cannabis packaging could look like as science continues to evolve. Whether you're a cannabis consumer, cultivator, scientist, budtender, regulator, or simply curious about how cannabis testing really works, this episode offers an evidence-based look at one of the industry's biggest conversations. CHAPTERS: 00:00 Meet Ben Cleary 01:04 Inside Village Farms 02:56 Why Study THC Variability 07:19 What the Data Shows 10:28 Range Based Labels 14:08 Low Dose Access Debate 16:37 Health Canada Pilot 19:06 Beyond THC Terpenes 22:56 Lighting and Scale Limits 30:31 Sampling Protocol Shortcut 33:23 Lab Testing Variability 35:26 Measured THC Reality 36:56 Quality Metrics Beyond THC 38:56 Industry Adoption Push 40:48 Why Village Farms Did It 43:05 Next Research Frontiers 45:11 Real World Data Approach 46:20 Science Community Stories 49:02 Medical Education Gap 52:50 Chemical Diversity Score Idea 56:15 Simplifying Labels for Consumers 57:39 Where to Follow the Research 59:40 Closing and BC Invite Read the Scientific Reports paper discussed in this episode:https://www.nature.com/articles/s41598-025-06962-2 Connect with Ben Cleary LinkedIn: https://www.linkedin.com/in/ben-cleary-746b00172/ Village Farms International: https://villagefarms.com/ Want Exclusive Content and ad-free episodes? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Sign Up for Emails! www.AppliedPharmacognosy.org Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 時間 3 分
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