5. Vitamin Chemistry: Isolating and Synthesizing Life's Catalysts
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5. Vitamin Chemistry: Isolating and Synthesizing Life's Catalysts
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Identifying a deficiency was the easy half of the problem. Drawing the molecule, and then making it by the ton, was the hard one. Paul Karrer's laboratory in Zurich looks less like a chemistry institute than a flower market, crates of crocuses and carrots waiting to be boiled down, and out of the colour he reads the first structure ever established for a vitamin. Adolf Windaus cracks a sterol ring open with ultraviolet light and gets vitamin D. Tadeus Reichstein hands the one step organic chemistry could not manage to a bacterium, and scurvy becomes an industrial fermentation. Roger Williams isolates pantothenic acid, the vitamin that turns out to be everywhere.
Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.
Pairs with Biochemistrypedia Chapter 15, Metabolism: Basic Concepts and Design - biochemistrypedia.com
The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.
Narrated by a digital voice.