Side effects. Adverse reactions. That folded-up piece of paper in your medication box with the tiny type nobody can read. That laundry list of horrible things in every drug commercial. This week, co-hosts Erin Stein and Dr. Gillian Goddard break down what all of it really means.

We start with the definitions: all side effects are adverse reactions, but not all adverse reactions are side effects. We explain how clinical trials sort side effects from coincidences with terms like “common,” “rare,” and “incidence not known.” We break down the actual numbers behind these categories and walk through a real medication’s side effect lists.

There is no medication without side effects, but side effects shouldn’t be your only consideration. We cover how to weigh benefits against the risks of doing nothing, when to stop a medication and call your doctor, and practical pharmacy tips: similar-sounding drug names, brand vs. generic, expiration dates, and why your medicine doesn’t belong in a steamy bathroom or your checked luggage.

We take a moment to remind you that while this is a medical discussion, it is not providing a diagnosis or treatment or any medical advice. The only way to get a diagnosis, treatment or medical advice for your particular condition is through a discussion with your doctor.

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This episode was produced and edited by Erin Stein. Music: “All We Live For (instrumental)” by Wolfclub licensed through Audiio.com. Intro and outro edited, and video created, by Ian Mayer. The Savvy Patient logo by Amanda Spielman.