#23 Pt1: Skeleton in the Closet - GLP-1s, Stress and Why Bone Loss Starts Decades Before You Expect
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#23 Pt1: Skeleton in the Closet - GLP-1s, Stress and Why Bone Loss Starts Decades Before You Expect
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Gary Rhodes, founder of Screen My Bones, opens a three-part deep dive into the most overlooked pillar of women's longevity: skeletal health. Part 1 covers what osteoporosis and osteopenia actually are, why bone loss in women accelerates so dramatically at menopause, and the hidden risks from GLP-1 weight loss drugs, chronic stress, and emotional trauma. Gary reversed his own grandmother's severe osteoporosis in 23 months — and has since scanned over 20,000 people to build the evidence base for early, proactive bone screening.
Key topics:
Reversing osteoporosis: Gary's grandmother's story (T-score minus 2.7 → normal range in 23 months)
What osteoporosis is — and why "disease" is the wrong framing
Bone density vs bone quality — two distinct measurements, both essential
T-scores, Z-scores, fragility scores: what to pay attention to
The menopause bone cliff: 1–5% loss per year, up to 20% over 5–7 years
Why women lose bone faster than men (oestrogen mechanism)
Osteoporosis prevalence: 19.6% in women vs 4.4% in men over 50
Peak bone mass at 28–32 and the case for screening in your thirties
GLP-1 drugs (Ozempic, Mounjaro) and the 40% muscle/bone loss risk
Osteoimmunology: bone marrow as immune factory; inflammatory cytokines and bone resorption
Cortisol, adrenal stress and mineral depletion from bone
Emotional trauma as a bone health risk factor
References and resources mentioned:
Screen My Bones: screenmybones.com
Tony Robbins — Unleash the Power Within (UPW): https://www.tonyrobbins.com/events/unleash-the-power-within
Dr Gabrielle Lyon — creatine and muscle protein research
Guest social links:
Website: screenmybones.com
Instagram (Gary Rhodes): https://www.instagram.com/garyandrewrhodes/
Instagram (Screen My Bones): https://www.instagram.com/screenmybones?igsh=MWY0ZWc1OWY1OGhubw==
Instagram (Screen My Bones US): https://www.instagram.com/screenmybones.us/
Instagram (Performance Health MSK): https://www.instagram.com/performancehealthsystemsmsk/
Facebook (Screen My Bones): https://www.facebook.com/profile.php?id=61566125690406
Facebook (Performance Health MSK): https://web.facebook.com/PerformanceHealthSystemsMSK
Insta/TikTok: @BiohackingEve
Website: www.BiohackingEve.com