10. Bioenergetics: Proton Gradients and ATP
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10. Bioenergetics: Proton Gradients and ATP
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Albert Lehninger pins oxidative phosphorylation to the mitochondrion. Peter Mitchell proposes that a cell's energy is stored as a difference in protons across a membrane, is told for the better part of two decades that this is theology rather than biochemistry, restores a manor house with his own hands while he waits, and is finally proved right. Paul Boyer works out that the enzyme making ATP does so by turning, and John Walker's crystals show the turning parts. Nathan Kaplan and Philip Handler build the field around them.
Season Two of We Are Biochemistry is the people behind the pathways, drawn from The Molecule Hunters, the book written by more than five hundred University of Virginia students.
Pairs with Biochemistrypedia Chapter 21, The Proton-Motive Force and ATP Synthase - biochemistrypedia.com
The full book, its sources, and the individual student credits are free at deppmannlab.com, where the corrections form also takes audiobook pronunciation fixes.
Narrated by a digital voice.