What actually changes when you start a GLP-1?

In Part 2 of our GLP-1 conversation, Jess shares her experience starting Zepbound (tirzepatide) after years of navigating PCOS, insulin resistance, prediabetes, and recurrent precancerous endometrial changes — and why deciding to try medication was a lot more complicated than simply wanting to lose weight.

We talk about the surprisingly complicated process of accessing GLP-1 medications, what Jess has noticed since starting Zepbound, and how things like food noise, hunger, fullness, alcohol, carbonation, and cravings can feel different.

Then we get into the messier, more nuanced stuff: inflammation, blood sugar, stress, sleep, diet culture, restriction, hunger cues, protein, fiber, muscle loss, hair loss, and learning to listen to your body when its signals may not feel the way they used to.

We also talk about the tension between intentional weight loss and trying not to fall back into restrictive or disordered patterns — because changing your body and taking care of your body aren't always as psychologically simple as they sound.

And, naturally, an intelligent conversation about fiber and constipation eventually turns into a detailed discussion of the Bristol Stool Chart. Because apparently this is who we are. 💩😂

CHAPTERS
00:00 🌪️ Welcome to the Chaos
00:47 💉 Jess’s GLP-1 Journey
05:49 🩺 Choosing a GLP-1 & Navigating Access
09:07 ✨ What Jess Has Noticed So Far
19:08 🔥 Inflammation, Sugar, & Food Choices
25:52 🧠 Hunger Cues, Restriction, & Finding Balance
31:57 🤔 Concerns: Muscle Loss, Hair Loss, & Side Effects
39:07 💩 Poop, Constipation, & the Bristol Stool Chart
45:51 🤏 Teeny Gripe, Tiny Delight
47:48 💜 Stay Curious. Stay Compassionate. Stay Loca.

⚠️ CONTENT NOTE: This episode includes discussion of weight, weight loss, body image, dieting and restriction, disordered eating patterns, medication side effects, and other health-related topics. Please take care of yourself while listening and skip anything that isn’t helpful for you.

🩺 DISCLAIMER: Living Luteal Loca is for educational and entertainment purposes only and is not a substitute for individualized medical advice, diagnosis, or treatment. We’re sharing our own experiences and perspectives, and GLP-1 medications are not right for everyone. Talk with a qualified healthcare professional about your individual health and treatment options.

🎵 Music: “Posy” — licensed through Soundstripe via Riverside

💜 Stay curious. Stay compassionate. Stay loca.