March Madness has begun and college basketball playoffs are heating up, not that Robert Walker - a graduate student from Texas - particularly cares. He has decided to skip classes for the day, sleep in, and get some rest. Unfortunately, a brief spat on the phone with his fiancée makes that impossible. Hoping to take his mind off of it, he scans through TV channels in search of entertainment and instead finds one news report after another that warns of violence erupting in the streets.

People are randomly and savagely attacking one another all along the East Coast from Maine to Florida. Some speculate it may be related to strange lights that have appeared in the sky above the outbreaks. Before any solid conclusions can be drawn, however, the brutality spreads, sweeping across the country until it hits Houston, then proceeds on to the West Coast. Robert, a handful of classmates, and a few others manage to survive the first wave and find themselves in the midst of civilization’s blackest hour, surrounded by pandemonium, bloodshed, and masses of people who have been stripped of their humanity. Hours later, as those strange lights continue to dominate the sky, the vicious horde undergoes a new transformation.

There is no escaping the horror. Unable to reach his fiancée by phone, Robert sets out to find her, joined by a small ensemble of fellow survivors. The thirty-five miles they must cover are fraught with danger, and their terror grows with each step they take as they witness the genesis of a new Earth. Can they find a way to stop it? Will they even survive it?