A classic thriller from #1 New York Times bestselling author Michael Crichton, Sphere is a bravura demonstration of what he does better than anyone: riveting storytelling that combines frighteningly plausible, cutting-edge science and technology with pulse-pounding action and serious chills.

The United States government is given a warning by the preeminent biophysicists in the country: current sterilization procedures applied to returning space probes may be inadequate to guarantee uncontaminated re-entry to the atmosphere.

In an age of political unrest, one man aims to bring the government to its knees—and there's only one agent who can stop him. Wealthy political radical John Wright has taken aim at the US government, believing that only he can make things right. State Department Agent John Graves has been watching Wright for months, studying him, gathering intel, trying to determine his next move before he makes it. Now, after hacking a government computer for secret files and stealing a shipment of VZ nerve gas, a binary agent, Wright has gathered everything he needs to unleash mass destruction.

In the tightly knit world of Boston medicine, the Randall family reigns supreme. When heart surgeon J. D. Randall’s teenage daughter dies during a botched abortion, the medical community threatens to explode. Was it malpractice? A violation of the Hippocratic Oath? Or was Karen Randall murdered in cold blood? The natural suspect is Arthur Lee, a brilliant surgeon and known abortionist, who has been carrying out the illegal procedure with the help of pathologist John Berry.

Ryland Grace is the sole survivor on a desperate, last-chance mission - and if he fails, humanity and the Earth itself will perish. Except that right now, he doesn't know that. He can't even remember his own name, let alone the nature of his assignment or how to complete it. All he knows is that he's been asleep for a very, very long time. And he's just been awakened to find himself millions of miles from home, with nothing but two corpses for company.