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The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

Taking a thematic rather than strictly chronological approach, W. F. Bynum, explores the key turning points in the history of Western medicine - such as the first surgical procedures, the advent of hospitals, the introduction of anesthesia, X-Rays, vaccinations, and many other innovations, as well as the rise of experimental medicine. The book also explores Western medicine's encounters with Chinese and Indian medicine, as well as nontraditional treatments such as homeopathy, chiropractic, and other alternative medicines.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.

This sweeping exploration of the impact of epidemic diseases looks at how mass infectious outbreaks have shaped society, from the Black Death to today, and in a new preface addresses the global threat of COVID-19. In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.

For much of recorded history, people considered the heart to be the most important organ in the body. In cultures around the world, the heart—not the brain—was believed to be the location of intelligence, memory, emotion, and the soul. Over time, views on the purpose of the heart have transformed. Modern medicine and science dismissed what was once the king of the organs as a mere blood pump subservient to the brain, yet the heart remains a potent symbol of love and health and an important part of our cultural iconography.

After the unprecedented events of the COVID-19 pandemic, it may be hard to imagine a time not so long ago when deadly diseases were a routine part of life. It is harder still to fathom that the best medical thinking at that time blamed these diseases on noxious miasmas, bodily humors, and divine dyspepsia. This all began to change on a day in April 1676, when a little-known Dutch merchant described bacteria for the first time. Ending Epidemics explains how we came to understand and prevent many of our worst infectious diseases—and double average life expectancy.

Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer's drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate United States authority on a drug's safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA's cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world.

The Right to Pain Relief and Other Deep Roots of the Opioid Epidemic offers a new lens through which to view the opioid epidemic as a consequence of serious misunderstandings of both opioids and pain. Based on their extensive research and experience with chronic pain care, science, ethics, and policy, the authors look beyond the usual villains—pharmaceutical companies and pharmacotherapy distributors—to examine the ethical and scientific concepts about pain that made the opioid epidemic possible.

Johns Hopkins University, one of the preeminent medical schools in the nation today, has played a unique role in the history of medicine. When it first opened its doors in 1893, medicine was a rough-and-ready trade. It would soon evolve into a rigorous science. In recent years, medical science has mapped the human genome, deployed robotic tools to perform delicate surgeries, and developed effective vaccines against a host of deadly pathogens. But this transformation could not have happened without the game-changing vision, talent, and dedication of a small cadre of individuals.

The Revolutionary War broke out during a smallpox epidemic, and in response, General George Washington ordered the inoculation of the Continental Army. But Washington did not have to convince fearful colonists to protect themselves against smallpox. In The Contagion of Liberty, Andrew M. Wehrman describes a revolution within a revolution, where the violent insistence for freedom from disease ultimately helped American colonists achieve independence from Great Britain.

In this book Steven Epstein analyzes the rise, proliferation, uptake, and sprawling consequences of sexual health activities, offering critical tools to assess those consequences, expand capacities for collective decision making, and identify pathways that promote social justice.

Antebellum New Orleans sat at the heart of America's slave and cotton kingdoms. It was also where yellow fever epidemics killed as many as 150,000 people during the nineteenth century. With little understanding of mosquito-borne viruses, a person's only protection against the scourge was to "get acclimated" by surviving the disease. Repeated epidemics bolstered New Orleans's strict racial hierarchy by introducing another hierarchy, what Kathryn Olivarius terms "immunocapital." Whereas immunity conferred privilege on whites, it relegated enslaved people to the most grueling labor.

In this panoramic account, we learn how great epidemics have not only led to enormous suffering and mass death but also changed the course of history. Humanity has struck back at the microbes: antibiotics and new vaccines have saved millions of lives. But the battle is far from won. We face increasing threats from new and unavoidable pandemics, antibiotic resistance, and even potential extraterrestrial microbes. Duel Without End is a fascinating journey through the long history of infection, from the dawn of life to humanity's future exploration of deep space.

One hundred years after a milestone medical discovery, Insulin: The Crooked Timber tells the story of how insulin was transformed from what one clinician called "thick brown muck" into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Taking the listener on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, the book reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes.

The Immune Mystery follows doctor and researcher Anita Kåss' quest to solve the autoimmune puzzle, beginning with the premature death of her mother, who developed rheumatoid arthritis shortly after giving birth to Anita. As a child, Anita vowed to study the illness and one day find a cure. Becoming a respected doctor and researcher, Anita devoted herself to studying autoimmune disorders like rheumatoid arthritis, lupus, and multiple sclerosis. A compelling blend of incredible determination and cutting-edge science, this book changes the way we think about autoimmune diseases.

When British-born Elizabeth Blackwell earned her medical degree in America in 1849, there was an international outcry. Few at the time would have disagreed with the actress Fanny Kemble's remark - "What, trust a woman doctor - never!"

The modern healthcare system has become proficient at staving off death with aggressive interventions. And yet, eventually everyone dies - and although most Americans say they would prefer to die peacefully at home, more than half of all deaths take place in hospitals or health care facilities. At the End of Life tackles this conundrum head on. Featuring 22 compelling personal-medical narratives, the collection explores death, dying, and palliative care, and highlights current features, flaws, and advances in the healthcare system.

Author Cory Franklin, MD, who headed the hospital's intensive care unit from the 1970s through the 1990s, shares his most unique and bizarre experiences, including the deadly Chicago heatwave of 1995, treating the first AIDS patients in the country before the disease was diagnosed, the nurse with rare Munchausen syndrome, the only surviving ricin victim, and the professor with Alzheimer's hiding the effects of the wrong medication.

Is it smart to skip your annual physical? Should you put your trust in medical research? Is "low T" an actual disease? This book will examine these questions and more you've always wondered about in a collection of 50 essays on the medicine. The Doctor Will See You Now is a quirky and eclectic collection of short essays that explore evolving patient-physician relationship and reporting on medicine; famous doctors and notorious patients; surprising hospital practices and the future of healthcare; medical research, ethics, drugs, and money; and the brave new world of neurology.