検索キーワード： 歴史・解説

He has been called the greatest surgeon of the 20th century. The son of Lebanese immigrants, Michael DeBakey rose from humble beginnings in a backwater Louisiana town to dominate the landscape of modern medicine. His contributions to our understanding and treatment of cardiovascular disease, in particular, were innumerable and epoch-making. DeBakey led a life of high drama, from the streets of Jazz Age New Orleans and the operating theaters of pre-war Europe, to the battlefields of World War II and the floodwaters of Hurricane Katrina.

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

Picking up where Berton Roueche's The Medical Detectives left off, The Deadly Dinner Party presents 15 edge-of-your-seat, real-life medical detective stories written by a practicing physician. Award-winning author Jonathan Edlow, MD, shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.

In World War II, 59,000 women voluntarily risked their lives for their country as US Army nurses. For more than half a century these women's experiences remained untold, almost without reference in books, historical societies, or military archives. After years of research and hundreds of hours of interviews, Evelyn M. Monahan and Rosemary Neidel-Greenlee have created a dramatic narrative that at last brings to light the critical role that women played throughout the war.

The gripping story of a chemical weapons catastrophe, the cover-up, and how one American Army doctor’s discovery led to the development of the first drug to combat cancer, known today as chemotherapy.

Against a global backdrop of wartime suffering and postwar hope, Borrowing Life gathers the personal histories of the men and women behind the team that enabled and performed the modern medical miracle of the world's first successful organ transplant.

In this extended lyric essay, a poet mines her lifelong experience with migraines to deliver a marvelously idiosyncratic cultural history of pain - how we experience, treat, and mistreat it. Her sources range from the trial of Joan of Arc to the essays of Virginia Woolf and Elaine Scarry to Hugh Laurie’s portrayal of Gregory House on House M.D. As she engages with science, philosophy, visual art, rock lyrics, and field notes from her own medical adventures (both mainstream and alternative), she finds a way to express the often-indescribable experience of living with pain.

Today, 90 percent of psychiatric beds are located in jails and prisons across the United States, institutions that confine disproportionate numbers of African Americans. After more than a decade of research, the celebrated scholar and activist Mab Segrest locates the deep historical roots of this startling fact, turning her sights on a long-forgotten cauldron of racial ideology: the state mental asylum system in which psychiatry was born and whose influences extend into our troubled present.

Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Michael Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent - and could easily be undone. Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.

Following the trail of an unexpected family connection, acclaimed journalist Pam Fessler has unearthed the lost world of the patients, nurses, doctors, and researchers at Carville who struggled for over a century to eradicate Hansen's disease, the modern name for leprosy. Amid widespread public anxiety about foreign contamination and contagion, patients were deprived of basic rights - denied the right to vote, restricted from leaving Carville, and often forbidden from contact with their own parents or children.

Just like us, medieval men and women worried about growing old, got blisters and indigestion, fell in love, and had children. And yet their lives were full of miraculous and richly metaphorical experiences radically different from our own, unfolding in a world where deadly wounds might be healed overnight by divine intervention, or where the heart of a king, plucked from his corpse, could be held aloft as a powerful symbol of political rule.

As a teenager, Molly Case underwent an operation that saved her life. Nearly a decade later, she finds herself in the operating room again - this time as a trainee nurse. She learns to care for her patients, sharing not only their pain, but also life-affirming moments of hope. In doing so, she offers a compelling account of the processes that keep them alive, from respiratory examinations to surgical prep, and of the extraordinary moments of human connection that sustain both nurse and patient.

Dr. Lange graduated from medical school in 1981, right as a new plague swept across the globe. His story became intertwined with the story of HIV. At once a physician, scientist, AIDS activist, and medical diplomat, Lange studied ways to battle HIV and prevent its spread from mother to child. Fighting the injustices of poverty, Lange advocated for better access to health care for the poor and the vulnerable. The Impatient Dr. Lange is the story of one man's struggle against a global pandemic - and the tragic attack that may have slowed down the search for a cure.

For Chinese immigrant Wong Chut King, surviving in San Francisco meant a life in the shadows. His passing on March 6, 1900, would have been unremarkable if a city health officer hadn't noticed a swollen black lymph node on his groin - a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong's tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed 10 million lives worldwide.

Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 "parrot fever" pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.

Hippocrates revolutionized the study of medicine in Ancient Greece, but some of his ideas still influence the medical field today. In his book On Ulcers, Hippocrates details the recommended treatment for this ailment. While modern medicine has moved beyond using honey, boiled leaves, and white wine to treat ulcers, Hippocrates’ advice on diet and rest hold true. This text is fascinating for anyone interested in the historical development of medical practices.

Hippocrates earned the title “Father of Medicine” for his extensive work in ancient Greece. He effectively established medicine as a profession. Modern doctors still swear to uphold the ethical standards he laid out in the Hippocratic Oath. His work On Surgery provides a fascinating look into medical history and the historical practices of this great physician.

A History of the Present Illness takes listeners into overlooked lives in the neighborhoods, hospitals, and nursing homes of San Francisco, offering a deeply humane and incisive portrait of health and illness in American today....In the tradition of Oliver Sacks and Abraham Verghese, Aronson's writing is based on personal experience and addresses topics of current social relevance. Masterfully told, A History of the Present Illness explores the role of stories in medicine and creates a world pulsating with life, speaking truths about what makes us human.

Now more than 133 million Americans live with chronic illness, accounting for nearly three-quarters of all health care dollars, and untold pain and disability. There has been an alarming rise in illnesses that defy diagnosis through clinical tests or have no known cure. Millions of people, especially women, with illnesses such as irritable bowel syndrome, chronic pain, and chronic fatigue syndrome face skepticism from physicians and the public alike.

Thought of as the seat of our soul, then as a mysteriously animated object, the heart is still more a mystery than it is understood. Why do most animals only get one billion beats? (And how did modern humans get to over two billion - effectively letting us live out two lives?) Why are sufferers of gingivitis more likely to have heart attacks? And what does it really feel like to touch your own heart, or to have someone else's beating inside your chest?

Maneater is a personal account by a specialist who approaches her work like a forensic scientist or a case-hardened private eye. Dr. Pamela Nagami is a leading authority on infectious diseases and her stories will shock, amaze, and warn listeners.The patients in Maneater are ordinary Americans. When Danielle Jordan innocently ordered a salad for lunch in Puerta Vallarta she had no idea she had just become the "host" to an organism that six years later would grow into a worm and burrow into her brain.

The "absorbing and powerful" (Wall Street Journal) story of two pioneering suffragette doctors who shattered social expectations and transformed modern medicine during World War I. In No Man's Land, Wendy Moore illuminates this turbulent moment of global war and pandemic when women were, for the first time, allowed to operate on men. Their fortitude and brilliance serve as powerful reminders of what women can achieve against all odds.

For centuries, doctors have struggled to define mental illness - how do you diagnose it, how do you treat it, how do you even know what it is? In search of an answer, in the 1970s a Stanford psychologist named David Rosenhan and seven other people - sane, normal, well-adjusted members of society - went undercover into asylums around America to test the legitimacy of psychiatry's labels. Rosenhan's watershed study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever.

Born in 1966 with a congenital heart defect known as the tetralogy of Fallot, Gabriel Brownstein entered the world just as doctors were learning to operate on conditions like his. He received a life-saving surgery at five years old, and since then has ridden wave after wave of medical innovation, a series of interventions that have kept his heart beating. The Open Heart Club is both a memoir of a life on the edge of medicine's reach and a history of the remarkable people who have made such a life possible.

By investigating thousands of descriptions of epidemics reaching back before the fifth-century-BCE Plague of Athens to the distrust and violence that erupted with Ebola in 2014, Epidemics challenges a dominant hypothesis in the study of epidemics, that invariably across time and space, epidemics provoked hatred, blaming of the "other", and victimizing bearers of epidemic diseases, particularly when diseases were mysterious, without known cures or preventive measures.

Government, industry, and the medical profession, however, have a mixed record when it comes to framing policies and generating knowledge to address drug use and misuse. In Strange Trips, Lucas Richert investigates the myths, meanings, and boundaries of recreational drugs, palliative care drugs, and pharmaceuticals as well as struggles over product innovation, consumer protection, and freedom of choice in the medical marketplace.

In Medical Bondage, Cooper Owens examines a wide range of scientific literature and less formal communications in which gynecologists created and disseminated medical fictions about their patients, such as their belief that black enslaved women could withstand pain better than white "ladies". Even as they were advancing medicine, these doctors were legitimizing, for decades to come, groundless theories related to whiteness and blackness, men and women, and the inferiority of other races or nationalities.

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.

Rabies enjoys a fearsome and lurid reputation. Throughout the decades of spiraling growth that defined New York City from the 1840s to the 1910s, the bone-chilling cry of "Mad dog!" possessed the power to upend the ordinary routines and rhythms of urban life. In Mad Dogs and Other New Yorkers, Jessica Wang examines the history of this rare but dreaded affliction during a time of rapid urbanization.