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The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

Through an unforgettable cast of characters, Pulitzer Prize-winning author Richard Rhodes explains how wood gave way to coal and coal made room for oil, as we now turn to natural gas, nuclear power, and renewable energy. Rhodes looks back on five centuries of progress, through such influential figures as Queen Elizabeth I, King James I, Benjamin Franklin, Herman Melville, John D. Rockefeller, and Henry Ford.

Populist rage, ideological fracture, economic and technological shocks, geopolitical dangers, and an international system studded with catastrophic risk—the early decades of the 21st century may be one of the most revolutionary periods in modern history. But they are not the first. Humans have lived, and thrived, through more than one great realignment. What makes an age a revolutionary one? And how do they end?

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

The daughter of a Buddhist priest, Tsuneno was born in a rural Japanese village and was expected to live a traditional life much like her mother’s. But after three divorces - and a temperament much too strong-willed for her family’s approval - she ran away to make a life for herself in one of the largest cities in the world: Edo, a bustling metropolis at its peak. With Tsuneno as our guide, we experience the drama and excitement of Edo just prior to the arrival of American Commodore Perry’s fleet, which transformed Japan.

In April 1970, during the glory days of the Apollo space program, NASA sent Navy Captain Jim Lovell and two other astronauts on America's fifth mission to the moon. Only 55 hours into the flight of Apollo 13, disaster struck: a mysterious explosion rocked the ship, and soon its oxygen and power began draining away. Written with all the color and drama of the best fiction, Apollo 13 (previously published as Lost Moon) tells the full story of the moon shot that almost ended in catastrophe.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Still considered one of the best books ever written about bullfighting, Death in the Afternoon reflects Hemingway's belief that bullfighting was more than mere sport. Here he describes and explains the technical aspects of this dangerous ritual, and "the emotional and spiritual intensity and pure classic beauty that can be produced by a man, an animal, and a piece of scarlet serge draped on a stick."

Most of us have instinctive evidence the world is ending - balmy December days, face-to-face conversation replaced with heads-to-screens zomboidism, a world at constant war, a political system in disarray. We hear some myths and lies so frequently that they feel like truths: Civilization is humankind’s greatest accomplishment. Progress is undeniable. Count your blessings. You’re lucky to be alive here and now. Civilized to Death counters the idea that progress is inherently good, arguing that the "progress" defining our age is analogous to an advancing disease.

With Frye as our raconteur-guide, we journey back to a time before barriers of brick and stone even existed - to an era in which nomadic tribes vied for scarce resources, and each man was bred to a life of struggle. Ultimately, those same men would create edifices of mud, brick, and stone and with them effectively divide humanity: On one side were those the walls protected; on the other, those the walls kept out. The stars of this narrative are the walls themselves - rising up in places as ancient and exotic as Mesopotamia, Babylon, Greece, China, Rome, Mongolia, Afghanistan, the lower Mississippi, and even Central America....

The Path Between the Seas tells the story of the men and women who fought against all odds to fulfill the 400-year-old dream of constructing an aquatic passageway between the Atlantic and Pacific oceans. It is a story of astonishing engineering feats, tremendous medical accomplishments, political power plays, heroic successes, and tragic failures. McCullough expertly weaves the many strands of this momentous event into a captivating tale.

Hillary Rodham Clinton and her daughter, Chelsea, share the stories of the gutsy women who have inspired them - women with the courage to stand up to the status quo, ask hard questions, and get the job done.

The most feared ship in Britain’s West Africa Squadron, His Majesty’s brig Black Joke was one of a handful of ships tasked with patrolling the western coast of Africa in an effort to end hundreds of years of global slave trading. Sailing after the spectacular fall of Napoleon in France, yet before the rise of Queen Victoria’s England, Black Joke was first a slaving vessel itself, and one with a lightning-fast reputation; only a lucky capture in 1827 allowed it to be repurposed by the Royal Navy to catch its former compatriots.  

For centuries, oceans were the chessboard on which empires battled for supremacy. But in the nuclear age, air power and missile systems dominated our worries about security, and for the United States, the economy was largely driven by domestic production, with trucking and railways that crisscrossed the continent serving as the primary modes of commercial transit.

Throughout history, humans have been driven by the quest for two cherished ideals: community and freedom. The two don’t coexist easily. We value individuality and self-reliance, yet are utterly dependent on community for our most basic needs. In this intricately crafted and thought-provoking book, Sebastian Junger examines the tension that lies at the heart of what it means to be human.

In the best-selling tradition of Hampton Sides’ In the Kingdom of Ice, a “gripping adventure tale” (The Boston Globe) recounting Dutch polar explorer William Barents’ three harrowing Arctic expeditions - the last of which resulted in a relentlessly challenging year-long fight for survival.

For 4,000 years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since common response to the threat was exclusion — quarantining the sick or keeping them out. But the unprecedented hygiene and medical revolutions of the past two centuries have allowed humanity to free itself from the hold of epidemic cycles — resulting in an urbanized, globalized, and unimaginably wealthy world.

In the best-selling tradition of Indianapolis and In Harm’s Way comes a “captivating...gripping” (Kirkus Reviews, starred review) account of the USS Plunkett - a US Navy destroyer that sustained the most harrowing attack on any Navy ship by the Germans during World War II, later made famous by John Ford and Herman Wouk.

In the 1930s, as official government expeditions set their sights on conquering Mount Everest, a little-known World War I veteran named Maurice Wilson conceives his own crazy, beautiful plan: He will fly a plane from England to Everest, crash-land on its lower slopes, then become the first person to reach its summit — completely alone.

As the dominant species on Earth, humans have made astonishing progress since our ancestors came down from the trees. But how did the descendants of small primates manage to walk upright, become top predators, and populate the world? How were humans able to develop civilizations and produce a globalized economy? Now, in The Age of Wood, Roland Ennos shows for the first time that the key to our success has been our relationship with wood.