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In July 1952, Dr. Walter Freeman arrived at the gates of a West Virginia asylum. In his medical bag he carried two metal picks and a surgical hammer. He had invented a “cheap, easy” ten-minute lobotomy. The press described it as a miracle cure, a new frontier in psychosurgery. That summer, in just twelve days, Freeman lobotomized 228 men, women, and children in West Virginia’s public mental hospitals. His blitzkrieg of brain surgery became known as “Operation Ice Pick,” named after the tools he wielded.

Dr. Ernst Gräfenberg was among the most sought-after gynecologists in pre-World War II Germany. The creator of the first IUD, known as the Gräfenberg ring, he was posthumously credited with identifying the eponymous "Gräfenberg spot" or G-spot. He was also a Jew in Nazi Germany, and by 1938 he had been stripped of his practice, his possessions, and his freedom and was languishing in a Nazi prison.

A possible genius, a smidgen of madness, a twist of science, and an invention that very nearly changed the world - all collide in a giddy, unbelievably true mystery set in turn-of-the-century Paris.