No published paper on Morgellons disease has ever investigated the geographic clustering of cases in Portland Oregon. This episode asks why.

Jesse Keller MD at Oregon Health and Science University OHSU is the only researcher in the United States conducting molecular bench science on Morgellons tissue. His 2023 paper in Archives of Dermatological Research found elevated oncostatin M expression in lesional skin biopsies of Morgellons patients compared to healthy controls. Oncostatin M is an inflammatory cytokine known to sensitize pain and itch neurons. His 2024 paper in British Journal of Dermatology documented that Morgellons patients report lower quality of life than patients with psoriasis atopic dermatitis and prurigo nodularis. Keller was featured on OPB Think Out Loud on March 10 2026 discussing Morgellons disease.

Referenced research: Keller Liu Latour 2023 Archives of Dermatological Research. Gipple Latour Keller Dhami 2024 British Journal of Dermatology. Pearson Vuolo Freire Merritt Klotter Maughan Montanez Amobi Middleton Dahlgren 2012 PLoS One CDC unexplained dermopathy study. Beuerlein Balogh Feldman 2021 Dermatology Online Journal. Akbarialiabad Salehi Murrell Jafferany 2025 Archives of Dermatological Research confirming zero randomized controlled trials exist for Morgellons treatment.

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