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Touching Base

Touching Base

著者： Genetic Engineering & Biotechnology News (GEN)
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 Touching Base is the dynamic podcast series from the editors of GEN (Genetic Engineering & Biotechnology News). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what's now and next.

Hosted on Acast. See acast.com/privacy for more information.

Genetic Engineering & Biotechnology News (GEN) 政治・政府 生物科学 科学
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  • Editors’ Choice: Top Stories of 2025

    Editors’ Choice: Top Stories of 2025
    2025/12/18
    In the final episode of 2025, the GEN team came together to reflect on some of the stories over the last year that they each found impactful. Some of the stories were covered in GEN’s December issue, but our editors took the time to discuss some topics in a bit more depth during the podcast. The discussion began with an update on the progress of AI use in drug discovery. Cell and gene therapy was a big topic with the positive outcome for Baby KJ, while Sarepta dealt with a rollercoaster of a year with their DMD treatment, Elevidys. Research and biotech in Africa are growing and the discussion ranged from challenges to promise in research and development on the continent. This year’s NIH budget cuts and impacted institutions rounded out the conversation.Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Fay Lin, Phd, Kevin Davies, Phd, John Sterling, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base: GEN Editors Reflect on Six of the Biggest Stories of the YearBy Alex Philippidis, Savannah Wiegel, Fay Lin, PhD, Kevin Davies, PhD, Uduak Thomas, and Julianna LeMieux, PhD, GEN, December 4, 2025StockWatch: Sarepta Says Deaths of Two Elevidys Patients Posted on FDA Database Unrelated to Treatment By Alex Philippidis, GEN Edge, August 10 StockWatch: As Prasad Exits FDA, Analysts See Benefit for Sarepta, CGT Stocks By Alex Philippidis, GEN Edge, August 3 FDA Probes Death of Brazilian Boy Linked to Sarepta’s Elevidys GEN Edge, July 27 Second DMD Patient Dies After Treatment with Sarepta Gene Therapy By Alex Philippidis, GEN Edge, June 15 DMD Patient Dies After Treatment with Sarepta Gene Therapy By Alex Philippidis, GEN Edge, March 18From The Editor in ChiefJohn Sterling, December Issue of GEN Gene Therapy in AfricaThe State of CRISPR & Genome Editing Summit, June 11, 2025TOP 50 NIH By Alex Philippidis, GEN, December 4, 2025 FDA Cell & Gene Therapy roundtable: Cell and Gene Therapy Leaders Tell FDA: “Believe in American Solutions” By Alex Philippidis, and Kevin Davies, PhD, GEN Edge, June 5, 2025Scientists in NYC Rally to Defend and Stand Up for ScienceBy Corinna Singleman, GEN, March 10, 2025Touching Base Podcast Hosted by Corinna Singleman, PhD Behind the Breakthroughs Hosted by Jonathan D. Grinstein, PhD Hosted on Acast. See acast.com/privacy for more information.
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    41 分
  • Lung Organoids, Autism and Sarcopenia Insights in Mice, and a Bidding War Ends

    Lung Organoids, Autism and Sarcopenia Insights in Mice, and a Bidding War Ends
    2025/12/04

    Stories on lung organoids and autism were some of the most read this week. We kicked things off by digging into recent breakthroughs in both areas including an automated method for manufacturing iPSC-derived lung organoids and how a combination of supplements reduced autism-linked behaviors in mice. Still on the topic of new research, we discussed how a protein in the extracellular matrix helps muscle stem cells repair aging muscles. In business news, the bidding war between Lundbeck and Alkermes over Avadel Pharmaceuticals has ended. We talk about the possible implications of Lundbeck’s decision to back out and next steps for Alkermes. Then we dive into Protego Biopharma’s recent fundraising round, and efforts to develop small-molecule pharmacological chaperones that modulate protein stability in disease.

    Join GEN editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news.

    Listed below are links to the GEN stories referenced in this episode of Touching Base:

    Lung Organoids Generated in Bulk Using Stirred Bioreactor Technology

    GEN, December 1, 2025


    Autism-Linked Behaviors in Mice Reduced by Nutrient Trio

    GEN, December 3, 2025


    Muscle Stem Cells Bolstered by ECM Protein Tenascin-C

    GEN, December 5, 2025

    Protego Closes $130M Series B to Fund Pivotal Trial of AL Amyloidosis Candidate

    By Alex Philippidis, GEN Edge, December 3, 2025

    Lundbeck Ends Bidding War for Avadel, After Alkermes’ Up-to-$2.37B Offer

    By Alex Philippidis, GEN Edge, December 1, 2025

    Touching Base Podcast

    Hosted by Corinna Singleman, PhD

    Behind the Breakthroughs

    Hosted by Jonathan D. Grinstein, PhD

    Hosted on Acast. See acast.com/privacy for more information.
    続きを読む 一部表示
    36 分
  • New Nasal Vaccines, Korro Stock Dips, J&J and Merck Acquisitions, and Dyno GATC

    New Nasal Vaccines, Korro Stock Dips, J&J and Merck Acquisitions, and Dyno GATC
    2025/11/20

    Nasal vaccines show new promise for human papillomavirus (HPV) to address cervical cancer and whooping cough. In business news, Korro's stock craters 81% as AATD interim Phase I/II results miss expectations. Additionally, Johnson & Johnson acquires Halda to expand their cancer pipeline while Merck acquires Cidara to boost antivirals. Lastly, the inaugural Genetic Agency Technology Conference (GATC) hosted by Dyno Therapeutics brought together a diverse group of researchers, entrepreneurs, and patient advocates to discuss the mission of genetic agency, or an individual’s ability to take action at the genetic level to live a healthier life.

    Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Fay Lin, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news.

    Listed below are links to the GEN stories referenced in this episode of Touching Base:

    Cervical Cancer May Be Treatable with Intranasal Nanogel Vaccine

    GEN, November 15, 2025


    Novel Nasal Spray Vaccine for Pertussis Shows Promise

    By Corinna Singleman, PhD, GEN, November 12, 2025

    StockWatch: Korro Craters 81% on Data; Patient Death Sours Analysts on Intellia

    By Alex Philippidis, GENEdge, November 16, 2025


    J&J Expands Cancer Pipeline with $3B Halda Acquisition

    By Alex Philippidis, GENEdge, November 18, 2025


    Merck to Acquire Cidara for $9.2B, Bolstering Antiviral Pipeline

    By Alex Philippidis, GEN, November 15, 2025

    AI Meets Genetic Agency at Dyno GATC 2025

    By Fay Lin, PhD, GENEdge, November 14, 2025


    Genetic Agency on Display at GATC 2025

    By Kevin Davies, PhD, and Fay Lin, PhD, GEN, November 13, 2025


    Dyno GATC Announces AI Agents, Muscle Capsid, and Manufacturing Partner

    By Fay Lin, PhD, GEN Edge, November 11, 2025

    Touching Base Podcast

    Hosted by Corinna Singleman, PhD

    Behind the Breakthroughs

    Hosted by Jonathan D. Grinstein, PhD

    Hosted on Acast. See acast.com/privacy for more information.
    続きを読む 一部表示
    42 分
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