At the turn of the 20th century, a severe burn was often a death sentence. Today, that is no longer the case. Over the past eighty years, burn care has undergone a profound transformation thanks to crucial advances across diverse areas of medicine, such as skin grafting, antiseptic technique, and fluid balance. In this episode, we trace how those pieces of the puzzle were integrated to bring new hope to those with severe burn injuries. But this revolution in burn care is far from over. As we discover, thrilling research in this area is blurring the lines between science and science fiction. Bioengineered skin? 3D-printed skin scaffolding? Nanoparticles? Tune in for all the exciting details!

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Burns have been a part of the human experience since our hominin relatives began controlling fire 1.5 million years ago. Until very recently, we’ve been limited in our ability to manage burn wounds with any success, having instead to rely on our body’s innate healing responses. In this episode, we delve into those repair responses, explore what makes burns different from other types of injuries, and examine how we categorize burns based on severity. On the history side of things, we take a tour through humanity’s quest to alleviate the pain and suffering caused by the near-universal experience of getting burned. Ever wondered what Hippocrates would have recommended for a burn? Or what distinguishes a second- from third-degree burn? Tune in to find out.

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An accurate diagnosis can give us so much. It can give us a path forward. It can give us answers to long-standing questions. And it can give us much-needed hope. Yet many people around the world wait years to receive an accurate diagnosis, which can take a profound physical and emotional toll. What underlies these missed or incorrect diagnoses, and what can we do about it? In this week’s TPWKY book club episode, health journalist Alexandra Sifferlin joins me to discuss The Elusive Body: Doctors, Patients, and the Diagnosis Crisis. Her compassionate and sweeping exploration of this topic takes readers across the US as she connects with patients, doctors, and researchers that are deeply impacted by the diagnosis crisis. While plumbing the depths of this pervasive issue, Sifferlin also encounters many people who have dedicated their careers to addressing the diagnosis crisis and bringing people the answers they need and deserve. Tune in for a fascinating conversation on a subject that has affected so many of us.

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