The streets are saying your T is low, your sperm is slow, and the count’s abysmal. What can you do about it? We called the Sperm King himself, Khaled Kteily, founder of Legacy, to break down why guys should think about sperm the way women think about eggs. He talks to us about revolutionizing sperm testing, freezing, and “de-risking your DNA” from the comfort of your home. Legacy is backed by celebrities like Justin Bieber and The Weeknd, and has frozen the sperm of more than a third of Fortune 100 CEOs. We answer important listener questions for Khaled like, “Did you enter your sperm in that sperm speed race competition?”. Give it a listen to find out.

P.S., Shout out to Legacy’s fractional general counsel. If your start-up needs legal support, look no further than Hosseini PPLC.

Sources + Required Reading

* FT: Who Broke the Sperm Bank?

This week, Ariana braves sugar withdrawals Upstate, Emily has seasonal allergies in BK, and Susana is…present? We investigate the world of designer babies, polygenic embryo screening, and the companies helping parents rate their embryos as hot or not. Is this lifestyle flex tiptoeing the ethical yellow caution tape between “wanting what’s best for your kid” and eugenics? If you’ve dropped thousands on frozen egg [commodity] futures or wondered if your future kid could beat your ex’s LSAT scores…this one’s for you.

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SOURCES + REQUIRED READING

Pfizer ends development of weight-loss pill danuglipron (Reuters, April 2025)

Novartis Press Release on US R&D pledge

Cofertility’s radical model for women: Freeze your eggs for free by donating half of them (Techcrunch, April 2025)

Should Human life be optimized (NYT, April 2025)

How to make a superbaby - start by screening your embryos (The Times, July 2024)

An IVF Alternative Could Make Having Babies Less Onerous (Wired, April 2025)

Embryo Screening and the Ethics of Human Genetic Engineering (Nature, 2008)

US startup charging couples to ‘screen embryos for IQ (The Guardian, October 2024)

Updates in preimplantation genetic testing (PGT) (Journal of Clinical Obstetrics & Gynaecology, 2024)

Who Broke the Sperm Bank (FT, March 2025)

How the unregulated sperm market is creating an online baby book (Newsweek, March 2025)

Episode Art Egg: The Substance

Was Adam (of Adam and Eve fame) patient zero in the male loneliness epidemic? In this episode, the ladies chat about social isolation and welcome their first guest, Producer Paul, to introduce some y-chromies and testosterone into the mix. We focus on the medicalization of loneliness, friend tech, and other budding business solutions to commodify connection. Your loss is their [capital] gain.

SOURCES

https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf

https://www.belonginstitute.com/courses/2025-in-person-community-building-intensive-2

https://www.statista.com/topics/11644/loneliness-in-the-us/

https://www.scienceofpeople.com/loneliness-statistics/

https://abcnews.go.com/Health/500-cases-measles-reported-nationwide-19-states-cdc/story?id=120251851

https://fortune.com/2025/03/28/23andme-bankruptcy-chapter-11-genetic-data-medical-ancestry-dna-silicon-valley-delete/

https://www.cbsnews.com/news/colorado-psychedelic-mushrooms-healing-centers/

https://www.jnj.com/media-center/press-releases/u-s-fda-approves-tremfya-guselkumab-the-first-and-only-il-23-inhibitor-offering-both-subcutaneous-and-intravenous-induction-options-for-adult-patients-with-moderately-to-severely-active-crohns-disease