As we close out Colorectal Cancer Awareness Month, this episode marks the final installment in our series on Lynch syndrome and hereditary cancer risk. If you haven’t yet, I encourage you to go back and listen to the earlier episodes—each one offers a powerful and important perspective on what it means to understand and navigate inherited cancer risk.

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Diane Hardesty’s story is one that clearly shows what can change when awareness meets action.

Before genetic testing, Diane’s family experienced ten cancer-related deaths connected to Lynch syndrome. Cancer wasn’t a possibility, it felt inevitable.

But once Diane chose to pursue genetic testing, everything shifted.

Through testing, proactive screening, and open family communication, her family has now experienced zero cancer-related deaths.

In this conversation, Diane shares her personal journey, the emotional weight of growing up with cancer as an expectation, and how one decision changed the trajectory for future generations.

This episode is a reminder that understanding your risk doesn’t create fear—it creates options.

• Family history matters more than many realize Patterns across generations can hold critical information about inherited cancer risk.
• Genetic testing can change outcomes Knowledge allows for earlier screening, prevention strategies, and informed decision-making.
• You are not only making decisions for yourself Testing and sharing information can directly impact children, siblings, and extended family.
• Prevention and early detection are powerful Diane’s family story shows what is possible when risk is understood and acted on.
• Conversations save lives Talking openly about cancer history within families is one of the most important steps people can take.

• Growing up in a family where cancer felt inevitable
• The moment Diane first learned about Lynch syndrome
• Deciding to pursue genetic testing
• What changed after her family began testing
• The emotional experience of learning her son did not inherit the mutation
• Advocacy, awareness, and speaking on a national stage
• Why sharing family health history is critical
• How awareness continues to evolve—and where gaps still exist

• AliveandKick’n (Lynch Syndrome advocacy and support) https://aliveandkickn.org
• FORCE (Facing Our Risk of Cancer Empowered) https://www.facingourrisk.org
• Jacqueline Rush Foundation - Lynch Syndrome Advocacy and Education https://www.jrushfoundation.org
• Lynch Syndrome Awareness & Education https://www.lynchsyndromeawareness.com
• National Society of Genetic Counselors (NSGC) – Find a genetic counselor https://www.nsgc.org
• NCCN Guidelines for Patients (Evidence-based screening guidance) https://www.nccn.org/patients
• My Faulty Gene (Advocacy + conference presence Diane supports) https://www.myfaultygene.org

Diane’s story is a powerful example of how knowledge can change a family’s future.

If cancer runs in your family, or if those conversations have never happened, this episode is a place to start.

🎧 The Positive Gene Podcast - https://thepositivegenepodcast.podbean.com/

IMPORTANT: This episode is for educational purposes and is not medical advice. Always consult your healthcare team for personal guidance.