Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/quick-take-1-cyclospora

Overview: Cyclospora infections in the US are running far ahead of a typical season, with thousands of suspected and confirmed cases across dozens of states as of mid-July 2026, and the source of the surge still under active investigation. In this Quick Take, we break down what primary care clinicians need to know right now: what this parasite is and how people get exposed, why the current outbreak dwarfs a usual season and why pinning down the source is so difficult, the clinical picture that should put cyclosporiasis on your differential, the testing pitfall that leads to missed diagnoses, and practical guidance for counseling patients on treatment, prevention, and what to expect as the investigation continues to unfold.

Learning Objectives:

1. Describe the biology and transmission of Cyclospora cayetanensis, and why 2026 is far from a typical cyclosporiasis season.
2. Identify the clinical features and exposure history that should raise suspicion for cyclosporiasis, and recognize the testing pitfall that causes routine stool panels to miss it.
3. Counsel patients on treatment, the prolonged course that often outlasts the parasite, prevention, and when to return for care.