Recorded at EHRA 2026, this episode of The Lead features host Christopher Kowalewski, MD, in conversation with Christian Sohns, MD, and Pierre Jaïs, MD, about the journal article, 20 Years: Clinical Outcome After Pulmonary Vein Isolation in Patients With Symptomatic Drug-Refractory Paroxysmal Atrial Fibrillation. Together, they discuss the study's long-term clinical outcomes following pulmonary vein isolation in patients with symptomatic drug-refractory paroxysmal atrial fibrillation and explore the implications of two decades of follow-up.

Learning Objectives:

• Review the long-term clinical outcomes reported after pulmonary vein isolation in patients with symptomatic drug-refractory paroxysmal atrial fibrillation.
• Discuss the implications of 20-year follow-up data for the treatment of patients undergoing pulmonary vein isolation.
• Examine how long-term outcome data may inform clinical decision-making for catheter ablation in paroxysmal atrial fibrillation.

Host: Christopher Kowalewski, MD

Guests: Christian Sohns, MD and Pierre Jaïs, MD

Disclosures:

C. Kowalewski

• No relevant disclosures

C. Sohns

• No relevant disclosures

P. Jaïs

• Ownership/Partnership/Prinicipal: inHEART
• Honoraria/Speaking/Consulting Fee: Biosense Webster, Inc., Boston Scientific, Medtronic

Recorded at EHRA 2026, this episode of The Lead features host Michael S. Lloyd, MD, FHRS, in conversation with Tina Baykaner, MD, MPH, and Kenneth Ellenbogen, MD, FHRS, about the journal article, Real-time smartphone alerts during atrial fibrillation episodes with implantable cardiac monitors and wearable devices: SMART-ALERT study. Together, they discuss the study findings and explore the use of real-time smartphone alerts in conjunction with implantable cardiac monitors and wearable devices during atrial fibrillation episodes.

Learning Objectives

• Review the design and key findings of the SMART-ALERT study evaluating real-time smartphone alerts during atrial fibrillation episodes.
• Discuss the use of implantable cardiac monitors and wearable devices for real-time detection and notification of atrial fibrillation episodes.
• Explore the potential clinical implications of integrating smartphone alerts with cardiac monitoring technologies.

Host: Michael S. Lloyd, MD, FHRS

Guests: Tina Baykaner, MD, MPH

Kenneth A. Ellenbogen, MD, FHRS

Disclosures:

M. Lloyd

· Honoraria/Speaking/Consulting Fee: Medtronic, Boston Scientific, Other

T. Baykaner

· Honoraria/Speaking/Consulting Fee: Volta Medical, Medtronic, Pacemate, Johnson & Johnson, Abbott Medical, Boston Scientific

· Research: NIH, Boston Scientific

K. Ellenbogen

· Honoraria/Speaking/Consulting Fee: American College of Cardiology, Heart Rhythm Society, Boston Scientific, Medtronic, Inc., Abbott

· Royalty Income: Wiley-Blackwell, Elsevier

Recorded at EHRA 2026, this episode of The Lead features host Michael S. Lloyd, MD, FHRS, in conversation with Tina Baykaner, MD, MPH, and Prashanthan Sanders, MBBS, PhD, FHRS, about the journal article, Atrial Mechanical Contraction Predicts Cerebrovascular Risk in Patients With Transthyretin Amyloid Cardiomyopathy and Sinus Rhythm. Together, they discuss the study findings and explore the relationship between atrial mechanical contraction and cerebrovascular risk in patients with transthyretin amyloid cardiomyopathy who are in sinus rhythm.

Learning Objectives:

• Review the key findings of the study examining atrial mechanical contraction and cerebrovascular risk in patients with transthyretin amyloid cardiomyopathy and sinus rhythm.
• Discuss the association between atrial mechanical contraction and cerebrovascular risk in this patient population.
• Explore the potential clinical implications of assessing atrial mechanical function in patients with transthyretin amyloid cardiomyopathy.

Host: Michael S. Lloyd, MD, FHRS

Guests:

Tina Baykaner, MD, MPH

Prashanthan Sanders, MBBS, PhD, FHRS

Disclosures:

M. Lloyd

• Honoraria/Speaking/Consulting Fee: Medtronic, Boston Scientific, Other

T. Baykaner

• Honoraria/Speaking/Consulting Fee: Volta Medical, Medtronic, Pacemate, Johnson & Johnson, Abbott Medical, Boston Scientific
• Research: NIH, Boston Scientific

P. Sanders

• Honoraria/Speaking/Consulting Fee: Boston Scientific, Abbott Medical
• Other Financial Relationships: Medtronic PLC, Pacemate, CathRx
• Research: Abbott, Becton Dickinson, Calyan Technologies, Ceryx Medical, Biosense Webster, CathRx, HelloAlfred, Medtronic, Inc., Abbott Medical