Mitochondrial dysfunction may be one of the most important topics in the area of personalized and preventative medicine to date. Thousands of articles have been published on the nature of how mitochondria become damaged and what that means for health, longevity, and aging. On today’s podcast, we take a deep dive into the triggers for mitochondrial dysfunction and what clinical conditions are related to damaged mitochondria.

We also discuss how to arm your arsenal with everyday items to help stability, protect, and maintain our mitochondria. We also discuss how other systems within and outside the cell are impacted by these “power plants” within.

Today on The Lab Report:

• 3:45 Break it down: the parts of the cell
• 8:40 The mitochondria are power plants
• 9:00 What’s normal?
• 10:00 Factors that trigger mitochondrial dysfunction
• 13:20 The mitochondria as our cell’s cohabitant
• 16:10 Progression of mitochondrial dysfunction
• 20:10 Clinical conditions associated with mitochondrial dysfunction
• 21:00 What can we do about it?

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Eggs are one of the most widely-consumed, and underappreciated, foods in the human diet. Long regarded as a nutritional powerhouse, eggs are rich in high-quality protein and essential nutrients that are key for health. In fact, eggs are considered the best complete protein – meaning they contain all 9 essential amino acids. But for decades, eggs were caught in the crossfire of the cholesterol debate.

In today’s episode, we’ll explore what current research says about the relationship between eggs and heart health, and whether concerns about dietary cholesterol still hold up. We’ll also discuss the role of eggs in weight management, muscle maintenance, eye health, and brain function. Whether you’re someone who eats eggs daily or has questions about whether you should, this episode offers a thoughtful, evidence-based discussion on why eggs have earned their place at the table.

Today on The Lab Report:

• 4:00 Why can't we agree about eggs?
• 6:00 Eggs are low calorie and a complete protein
• 8:30 Which is better the whites or the yolks?
• 10:00 Eggs, choline, and brain health
• 11:45 Eggs and eyes
• 17:00 The egg and cholesterol controversy
• 19:45 We find a way to bring "methylation" into the discussion
• 23:00 Eggs, satiety, and weight management
• 24:50 Little known constituents inside eggs
• 26:30 Other types of eggs and their nutritional value
• 29:00 Fun facts about eggs: color and bloom
• 30:20 Which came first, the chicken or the egg?

We also referenced The Methylation Episode which can be listened to here.

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Stool testing technology has advanced rapidly in recent years, with newer methods like PCR and whole-genome sequencing offering faster and more precise insights into the gut microbiome. These innovations have transformed how clinicians approach gut health, allowing for more targeted interventions. However, older technologies—such as microscopy, culture, and enzyme-based assays—still play a valuable role. These methods provide functional insights that molecular tools may miss, such as direct observation of parasites or assessment of digestive markers. The most comprehensive labs recognize that no single method gives the full picture. Instead, combining the strengths of both modern and traditional techniques ensures more accurate, clinically meaningful results.

In this episode, we dive into the pros and cons of different laboratory methodologies used in stool testing—from culture and microscopy to PCR and advanced sequencing. We break down how these choices impact accuracy, sensitivity, and clinical usefulness. You'll also learn why Genova Diagnostics stands out for its integrative, evidence-based approach, combining multiple testing methods to deliver the most comprehensive and clinically actionable results available.

Today on The Lab Report:

• 4:00 Technology grows quickly, and the microbiome is complex
• 7:30 Microbiology culture
• 12:40 PCR – very precise if done correctly!
• 17:00 Interpreting the laundry list
• 20:10 Remember the microscope?
• 23:30 Whole-genome (shotgun) sequencing pros/cons
• 27:15 Genova does it all – and well

Additional Resources:

GI Effects Stool Profile

Microbiomix

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.