『The Human Upgrade: Biohacking for Longevity & Performance』のカバーアート

The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

著者： Dave Asprey
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For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

© Copyright © Bulletproof Media 2023 個人的成功 科学 自己啓発 衛生・健康的な生活
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  • Biohacking Cannabis: The DNA Science of Plant Medicine : 1353

    Biohacking Cannabis: The DNA Science of Plant Medicine : 1353
    2025/10/28
    Discover how decoding your DNA can unlock the full potential of plant medicine. This episode delivers a cannabis masterclass for biohackers, revealing how personalized genetics are transforming human performance, brain optimization, and longevity. You’ll learn how to identify your ideal cannabis and supplement protocols, balance your endocannabinoid system, and turn precision data into powerful healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Len May, MSc, visionary authority in personalized medicine and CEO of EndoDNA, the world leader in DNA-based wellness technology. With over 25 years of pioneering work in genomics, epigenetics, and medicinal cannabis, Len’s patented DNA decoding system maps your unique genotypes to design tailor-made health solutions. His company holds the world’s largest real-world efficacy database in precision wellness, integrating functional medicine, AI-driven analytics, and genetic data to create personalized blueprints for optimal brain function and performance. Together, Dave and Len explore how your genetic code determines how you respond to cannabis, psychedelics, nootropics, and supplements—and how to use that data to reduce anxiety, improve sleep optimization, and enhance focus. You’ll learn how decoding your DNA can guide anti-aging strategies, mitochondrial performance, metabolism, and neuroplasticity, revealing new ways to live longer and smarter. This episode dives deep into the intersection of cannabis science, genomics, and biohacking. You’ll discover how genetic polymorphisms influence mood, cognition, and stress response, and how personalized medicine can help you make smarter decisions around ketosis, fasting, and recovery. From optimizing the endocannabinoid system to hacking your biology for resilience and longevity, this is the future of functional medicine in action. You’ll Learn: • How the endocannabinoid system regulates mood, focus, pain, and stress response • Which genetic polymorphisms affect cannabis sensitivity, anxiety risk, and dosing windows • How to use DNA testing to select cannabinoid and terpene ratios that fit your biology • Why delivery method matters and when sublingual dosing outperforms inhalation • How personalized cannabis protocols can support sleep optimization, recovery, and emotional regulation • The role of cannabinoids in mitochondrial function, neuroplasticity, and cognitive performance • How pharmacogenomics reduces antidepressant side effects and improves treatment matching • How to screen genetics for safer psychedelic use and avoid adverse reactions • What HLA and related markers reveal about mold sensitivity and inflammation This is essential listening for anyone serious about biohacking, brain optimization, longevity, anti-aging, functional medicine, and living Smarter Not Harder—with precision tools designed to upgrade your mind and body at the genetic level. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cannabis biohacking, cannabis masterclass, Dave Asprey cannabis, DNA decoding, genetic testing for cannabis, personalized medicine, endocannabinoid system, cannabis genomics, cannabis and DNA, cannabis and genetics, cannabis nootropics, plant medicine biohacking, cannabis brain optimization, cannabis and neuroplasticity, cannabis for focus, cannabis and mitochondria, cannabis metabolism, cannabis for sleep, cannabis anti-aging, precision wellness, functional medicine, cannabis longevity, EndoDNA, Len May, cannabis and AI, biohacking genetics, cannabis and fasting, cannabis and ketosis, personalized supplements, cannabis and mood, cannabis stress response, genetic biohacking, cannabis cognitive performance Thank you to our sponsors! -Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -iRestore | Use code DAVE at https://www.irestore.com/ to unlock an exclusive discount on the iRestore Elite. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND...
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    43 分
  • This Legal Focus Powder Beats Any Dopamine Detox : 1352

    This Legal Focus Powder Beats Any Dopamine Detox : 1352
    2025/10/26

    Dopamine isn’t the enemy—low brain energy is. When your mitochondria can’t make enough ATP, your neurons misfire, leading to fatigue, brain fog, and lack of focus. In this video, I explain why dopamine problems are really energy problems, how mitochondrial health drives motivation and clarity, and why creatine is one of the most effective and affordable nootropics for restoring mental performance. Learn the biohacks that protect your brain’s power plants and keep you sharp all day long.


    Chapters

    0:00 – Introduction

    0:22 – Brain energy vs dopamine

    0:49 – ATP shortage causes fatigue

    1:53 – Prefrontal cortex and energy

    3:08 – Why ATP fuels focus and mood

    4:40 – Stress, sleep and mitochondria

    6:00 – Biohacks for energy production

    7:39 – Backup battery: phosphagen system

    8:46 – Creatine for brain energy & focus

    13:18 – Vegans, women and creatine needs

    15:07 – Best practices for dosing creatine

    17:53 – Daily creatine + electrolytes


    Thank you to our sponsors!

    -ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask.


    Connect with Dave Asprey!


    Website: https://daveasprey.com

    TikTok: https://www.tiktok.com/@daveaspreyofficial

    Instagram: https://www.instagram.com/dave.asprey/

    Facebook: https://www.facebook.com/Daveaspreyofficial/

    X: https://x.com/daveasprey

    YouTube: https://www.youtube.com/c/daveaspreybpr


    The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/


    Danger Coffee: https://dangercoffee.com/DAVE15

    Dave Asprey’s BEYOND Conference: https://beyondconference.com/

    Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

    Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15

    Upgrade Collective: https://www.ourupgradecollective.com

    Upgrade Labs: https://upgradelabs.com

    40 Years of Zen: https://40yearsofzen.com

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    18 分
  • Biohacking News Weekly Update : 1351

    Biohacking News Weekly Update : 1351
    2025/10/24
    Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. This episode breaks down the five biggest stories in biohacking and health-tech — from genetic rejuvenation to your future digital twin — giving you the tools to live longer, perform better, and stay ahead of the curve.This episode covers:• Vitamin D as the Surprising “Anti-Aging Pill”A new five-year randomized study shows that daily 2,000 IU vitamin D supplementation slowed telomere shortening by 140 base pairs compared to placebo, translating to measurable gains in biological youth. Vitamin D isn’t just for bones anymore — it’s a foundational longevity molecule.Source: Science Daily — https://www.sciencedaily.com/releases/2025/10/251022023132.htm• The Supercentenarian Gene That Rejuvenates Old HeartsResearchers at the University of Bristol identified a gene variant, LAV-BPIFB4, common among people living past 100, that reversed cardiac aging in animal studies — restoring blood flow, heart strength, and tissue repair with a single treatment. It’s a glimpse into how gene therapy could soon democratize superhuman longevity.Source: University of Bristol News — https://www.bristol.ac.uk/news/2025/october/progeria.html• FDA Closes the “GRAS” Loophole — Supplements Enter a New EraThe FDA just ended decades of self-certification for new dietary ingredients, requiring full agency review for anything entering the market. It’s the biggest shakeup in supplement regulation in years — raising quality, accountability, and trust across the entire industry.Source: Mintz FDA Flux Newsletter — https://www.mintz.com/insights-center/viewpoints/2791/2025-10-16-fda-flux-october-2025-newsletter• Microbes That Trigger Autophagy — Your Gut as an Anti-Aging SwitchScientists at the University of Basel discovered that certain dietary bacteria containing double-stranded RNA can directly trigger autophagy, the body’s built-in cell-recycling system. Fermented foods like kimchi, kefir, and sauerkraut may now be proven longevity tools for activating repair from the inside out.Source: University of Basel — https://www.unibas.ch/en/News-Events/News/Uni-Research/Longevity-research—Dietary-stress-supports-healthy-aging.htmlFurther reading: Neuroscience News — https://neurosciencenews.com/dietary-rna-cellular-aging-29757/• Your Medical Avatar Is Coming — The Digital Twin of YouForbes reports on the rise of personalized “medical avatars” — AI-powered digital twins built from your wearables and biometrics that can predict health risks, recommend interventions, and evolve alongside your biology. Doctors like Daniel Kraft call it generative health — a revolution in predictive medicine where your data literally becomes your doctor.Source: Forbes Innovation — https://www.forbes.com/sites/johnwerner/2025/10/21/wearables-ai-and-your-personal-medical-avatar/This is essential listening for fans of biohacking, human performance, functional medicine, and longevity sciencewho want real, actionable tools from Dave Asprey — the father of biohacking and founder of Bulletproof Coffee.With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your lifespan, and upgrade every system in your body and mind.New episodes drop every Tuesday, Thursday, Friday, and Sunday. Dave asks the questions no one else will — and gives you the science-backed tools to become stronger, smarter, and more resilient.Keywords: vitamin D longevity, telomeres, BPIFB4 gene, cardiac rejuvenation, supplement regulation, GRAS FDA, autophagy, microbiome, fermented foods, biohacking news, medical avatar, digital twin, predictive medicine, Daniel Kraft, quantum health, wearable AI, Dave Asprey, The Human UpgradeThank you to our sponsors! TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off.HeartMath | Go to https://www.heartmath.com/dave to save 15% off.Timestamps: 0:00 — Introduction0:18 — Story 1: Vitamin D & Telomeres1:02 — Story 2: Longevity Gene Therapy1:49 — Story 3: FDA Supplement Reform2:38 — Story 4: Gut Bacteria & Autophagy3:46 — Story 5: Medical Avatars4:53 — Weekly Protocol5:42 — OutroSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    6 分
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