Mindfulness, Medicine & the Biology of Stress explores how meditation can change our relationship to stress, support the body's natural healing systems, and help us live with more presence, compassion, and ease.

In this episode of The FitMind Podcast, we sit down with Craig Hassed, MD, physician, educator, and mindfulness expert, to examine the science and practice of mind-body medicine. Drawing from decades of clinical work, teaching, and contemplative practice, Craig explains how chronic stress creates physiological wear and tear in the body, known as allostatic load, and why learning to return to the present moment can have effects far beyond feeling calmer.

The conversation explores how mindfulness may influence inflammation, immune function, gene expression, and biological aging, including research on telomeres and the body's stress circuitry. Craig also discusses why informal mindfulness in daily life may be just as important as formal meditation practice, especially when we are caught in worry, pressure, or mental projections about the future.

Topics include:

• How mindfulness became part of the medical curriculum at Monash University
• Why chronic stress creates wear and tear on the body
• What allostatic load means for health and aging
• How meditation may affect inflammation, immunity, and gene expression
• The relationship between mindfulness and telomeres
• Why presence can improve focus, performance, and flow
• The difference between empathy, empathic distress, and compassion
• Why compassion may protect against burnout
• How mindfulness can support doctors, patients, students, and everyday life
• The question of consciousness and whether it may be more fundamental than matter

A practical and wide-ranging conversation for anyone interested in the medical science of mindfulness, the biology of stress, or how contemplative practice can support resilience, compassion, and human flourishing.

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Liam's book, Fit Mind, is now available! You can pick up a copy and learn more at fitmind.org/book.

FitMind Neuroscience-Based App: http://bit.ly/afitmind

Website: www.fitmind.org

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Show Notes

0:00 | Introduction to Dr. Craig Hassed
3:23 | Discovering meditation without a teacher
9:18 | Bringing mindfulness into clinical medicine
10:21 | Teaching mindfulness to medical students
15:10 | How chronic stress affects the body
15:56 | Understanding allostatic load
20:57 | Epigenetics, inflammation, and immune function
22:42 | Meditation, telomeres, and biological aging
26:17 | How much meditation is enough?
29:18 | Formal practice vs. mindfulness in daily life
31:17 | The growth of mindfulness research
36:54 | The ESSENCE model of health
38:56 | Choosing the right meditation practice
41:47 | How the mind creates unnecessary stress
45:21 | Mindfulness, performance, and flow states
51:21 | Mindfulness education and human flourishing
52:40 | Technology, isolation, and genuine connection
1:00:43 | Empathy, empathic distress, and compassion
1:01:42 | Why compassion may protect against burnout
1:06:16 | Is consciousness more fundamental than matter?
1:07:10 | Can consciousness be scientifically measured?
1:08:33 | Craig's daily practice and rapid-fire questions
1:09:15 | Final thoughts

Zen & the Science of Living Well with Robert Waldinger, MD explores what the longest-running study of adult life reveals about happiness, health, connection, and the many different ways a meaningful life can unfold.

In this episode of The FitMind Podcast, we sit down with Robert Waldinger, MD, psychiatrist, Zen teacher, and director of the Harvard Study of Adult Development, to examine what actually helps people thrive over the course of a lifetime. Drawing from more than eight decades of research, Robert explains why strong relationships are one of the clearest predictors of long-term health and happiness, and how loneliness can affect the body through chronic stress, inflammation, and nervous system dysregulation.

The conversation also explores the overlap between psychotherapy, lifespan research, and Zen practice. Robert discusses why there is no single formula for a good life, how the mind fills in the blanks when faced with uncertainty, and why equanimity is not emotional suppression, but a wiser relationship to reactivity.

Topics include:

• How the Harvard Study of Adult Development tracks happiness across a lifetime
• Why relationships are deeply linked to health and longevity
• How loneliness can become a chronic stressor in the body
• The difference between solitude and loneliness
• What people most often regret near the end of life
• How Zen and psychology both reveal the stories the mind creates
• Practical ways to build "social fitness" in everyday life

A grounded, expansive conversation for anyone interested in the science of happiness, the health effects of connection, or how contemplative practice can help us live with more presence, meaning, and care.

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Liam's upcoming book, Fit Mind, is now available for preorder. You can learn more at fitmind.org/book.

FitMind Neuroscience-Based App: http://bit.ly/afitmind

Website: www.fitmind.org

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Show Notes

0:00 | Merging Zen, science, and psychotherapy

3:18 | Breaking the silence on personal spiritual practice

6:12 | Overview of the Harvard Study of Adult Development

9:53 | How chronic loneliness breaks down physical health

13:09 | Evolutionary biology of group connection and safety

15:10 | Many paths to a good life: unconventional contentment

19:17 | Vulnerability and the myth of the self-made man

21:35 | Research-backed strategies for building new friendships

24:23 | End-of-life regrets and sources of pride

26:08 | Resume values vs. eulogy values

28:02 | Noticing and transforming internal self-criticism

32:52 | The WISER model for slowing down social reactions

39:32 | Equanimity: feeling deeply without reactive explosion

42:11 | Subjective loneliness vs. the contentment of solitude

48:23 | Practical exercises: gratitude, subtraction, and nature

51:44 | Social fitness and the impact of digital habits

55:52 | The future of human connection in the age of AI

1:01:21 | Closing reflections and the upcoming book Nothing to Fix

The Illusion of Self: Nondual Meditation & Brain Science with John Dunne, PhD explores how our sense of identity is constructed moment by moment, drawing on Buddhist philosophy, neuroscience, and contemplative practice to explain why thoughts feel real and how seeing through them can fundamentally change our experience.

In this episode of The FitMind Podcast, we sit down with John Dunne, PhD—a leading scholar-practitioner bridging ancient wisdom and modern science—to examine the nature of mind, self, and awareness. Rather than treating thoughts as accurate reflections of reality, John frames them as useful but often misleading constructions shaped by the brain's attempt to predict and navigate the world.

We explore how meditation helps us "de-reify" thoughts—seeing them as mental events rather than truths—and why this shift may be central to reducing anxiety and depression. John also breaks down non-dual traditions like Mahamudra and Dzogchen, offering a clear lens into practices aimed not at changing experience, but at recognizing its underlying nature.

Topics include:

• How the brain constructs a sense of self through predictive models
• Why thoughts feel real and how to see through them
• The role of meditation in shifting our relationship to thinking
• Differences between gradual and non-dual approaches to practice
• What "effortless awareness" means and why it matters
• Scientific insights from studying advanced meditators

A grounded, intellectually rich conversation for anyone interested in understanding the mind more clearly, working with difficult thoughts, or exploring the intersection of neuroscience and contemplative practice.

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Liam's upcoming book, Fit Mind, is now available for preorder. You can learn more at fitmind.org/book.

FitMind Neuroscience-Based App: http://bit.ly/afitmind

Website: www.fitmind.org

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Show Notes

0:00 | From astronaut dreams to inner exploration
2:40 | Introducing John Dunne and his background
5:30 | Identity crisis and discovering meditation
9:30 | Early practice: Vipassana, metta, and analytical meditation
14:30 | Questioning reality and the nature of self
19:30 | Concepts, language, and why thoughts feel real
25:30 | How the mind constructs identity moment to moment
31:30 | Mahamudra and Dzogchen: gradual vs non-dual paths
38:30 | Effort vs effortlessness in meditation
45:00 | Anxiety, depression, and predictive processing
50:30 | De-reification: seeing thoughts as thoughts
56:30 | Watching the mind vs being lost in it
1:01:30 | Brain studies with advanced meditators
1:07:00 | Non-dual awareness and "always-on" presence
1:12:30 | What enlightenment is (and isn't)
1:17:30 | Tukdam and the mystery of consciousness at death
1:22:30 | Science, meditation, and open questions
1:25:30 | Closing reflections