Dr. David Perlmutter — neurologist, New York Times bestselling author, and author of the new book Brain Defenders — joins Dr. Will Cole to reveal what he believes is the most important breakthrough in brain health science in decades: the microglial cell. He explains why the amyloid hypothesis that has dominated Alzheimer's research (and pharmaceutical spending) for 30 years has been definitively disproven by a Cochrane analysis, why a Harvard lifestyle study arrested Alzheimer's decline in 70% of patients without any drug, and what the April 2024 NEJM GLP-1 Parkinson's trial means for the future of neurodegenerative disease. They also cover the practical daily habits, foods, supplements, and lab tests that shift the brain's immune cells from destructive to protective — and why you are far more the architect of your brain's destiny than anyone has told you. For all links mentioned in this episode, visit http://www.drwillcole.com/podcast

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