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  • Innovative Approaches to Abdominal Cancer: A Deep Dive into HIPEC and PIPAC with Dr. Byrne Lee

    Innovative Approaches to Abdominal Cancer: A Deep Dive into HIPEC and PIPAC with Dr. Byrne Lee
    2026/04/01
    In this episode of Scrubcast, host Rachel Baker speaks with Dr. Byrne Lee, a clinical professor specializing in surgical oncology at Stanford University. Dr. Lee shares his personal connection to cancer, discussing how family experiences have shaped his dedication to the field. The episode delves into innovative treatments such as Heated Intraperitoneal Chemotherapy (HIPEC) and the emerging technique of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC), highlighting their roles in treating cancers that have spread to the abdominal cavity. Dr. Lee emphasizes the importance of a patient-centered approach in cancer care, offering insights into the evolving landscape of treatment options and the crucial role of multidisciplinary collaboration in improving patient outcomes. Listeners will gain a deeper understanding of not only the technical aspects of these advanced therapies but also the emotional and ethical considerations that accompany cancer treatment. Through personal anecdotes and professional insights, Dr. Lee inspires hope and resilience in the face of challenging diagnoses. Link to “Results of the First Phase I PIPAC Trial in the United States: Braving the Storm:” https://link.springer.com/article/10.1245/s10434-023-14353-y
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    21 分
  • Where Cancer and Cardiovascular Health Meet with Dr. Nazish Sayed

    Where Cancer and Cardiovascular Health Meet with Dr. Nazish Sayed
    2026/03/02
    Scubcast welcomes back Dr. Nazish Sayed, an associate professor in the Division of Vascular Surgery, for a discussion on the latest research in cardio vascular health. In this episode, Dr. Sayed reflects on the enduring benefits of statins, delves into the intricacies of tyrosine kinase inhibitors and their effects on vascular endothelial cells, and introduces innovative approaches in studying vascular Ehlers Danlos syndrome. He also shares personal experiences as both a clinician and cancer survivor, shedding light on the emotional journey of patients navigating "scanxiety." Tune in to explore cutting-edge advancements in cardio-oncology and precision medicine that promise to improve patient care and outcomes in this fascinating field.
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    20 分
  • Exploring the Intersection of Surgery and Cancer Research with Dr. Dan Delitto

    Exploring the Intersection of Surgery and Cancer Research with Dr. Dan Delitto
    2026/02/02
    Dr. Dan Delitto is an assistant professor of surgery at Stanford University specializes in surgical oncology and holds a PhD in immunology. On this episode, Dr. Delitto reflects on his decision to pursue an MD-PhD pathway during residency and discusses the recent advancements in single-cell RNA sequencing technology that his lab has acquired. He explains the complex role of fibroblasts in cancer development, particularly in pancreatic ductal carcinoma, highlighting how these cells can both promote and hinder tumor growth. The conversation includes a lightning round, during which Dr. Delitto shares his admiration for his mentor, Steve Hughes, and offers succinct advice on the importance of surgical experience. He also mentions his preference for trance music while working and shares his excitement about ongoing and future research projects in his lab, which include investigations into various cancers, such as sarcomas. Link to Nature Cancer article “Cancer-derived mitochondria fuel fibroblasts to become pro-tumorigenic.”: https://www.nature.com/articles/s43018-025-01005-1 Link to Cell Reports article “Disruption of fibroblast MYD88 signaling promotes antitumor immunity in pancreatic ductal adenocarcinoma”: https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01118-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124725011180%3Fshowall%3Dtrue
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    14 分
  • 20 years of Improving Transplant Tolerance with Dr. Stephan Busque

    20 years of Improving Transplant Tolerance with Dr. Stephan Busque
    2025/12/01
    This episode features Stanford Professor and transplant surgeon Dr. Stephan Busque. He discusses his extensive experience in the field of tolerance in transplantation, particularly focusing on advancements over the past 20 years. Dr. Busque highlights the significance of his team's work on translating research into clinical practice and mentions that they have the largest experience globally in this field. Additionally, Dr. Busque shares exciting news about Stanford's first allogenic islet cell transplantation for a patient with type one diabetes, indicating a collaborative effort that brought together a multidisciplinary team to achieve this milestone. He reflects on the journey of making islet cell transplants more accessible and expresses hope for new beginnings in this area. The episode wraps up with a lightning round where Dr. Busque discusses the qualities he admires in skilled surgeons, emphasizing the importance of being a well-rounded doctor who not only excels in technical skills but also demonstrates a deep understanding of patient care and connection. Going forward he’s excited for the development of protocols for various transplant scenarios, including open liver transplant tolerance, and indicates that patients with less-than-perfect matches are the next target group for improvements in transplantation techniques
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    30 分
  • Crohn's Disease and Creeping Fat with Dr. Jeong Hyun

    Crohn's Disease and Creeping Fat with Dr. Jeong Hyun
    2025/11/03
    On this episode of Scrubcast, episode of Scrubcast features Dr. Jeong Hyun, an assistant professor in the division of pediatric surgery at Stanford University, discusses his journey to becoming a surgeon scientist. Hyun’s research is focused on Crohn's disease and how strictures develop in the intestines. Shout out to MD/PhD candidate Khristian Bauer-Rowe, who he collaborated with on the September article in Cell looking at the role of creeping fat and CTHRC1+ fibroblasts. The episode also touches on Dr. Hyun's personal interests, including his unexpected love for country music, which he developed while working in Kansas City. The discussion concludes with Dr. Hyun acknowledging the uncertainties in research funding and the importance of vulnerability and resilience in both personal and professional life. Link to article: https://www.cell.com/cell/abstract/S0092-8674(25)01018-9
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    28 分
  • Advancements in Breast Cancer Treatment with Dr. Fred Dirbas

    Advancements in Breast Cancer Treatment with Dr. Fred Dirbas
    2025/10/01
    On this episode of Scrubcast, we speak with Dr. Fred Dirbas, the John and Ann Doerr Faculty Scholar of Breast Surgery and chair of the breast disease site working group for the Society for Surgical Oncology. Rather than ascribing to a particular set of screening recommendations, Dr. Dirbas advocates for personalized screening strategies, particularly for women with a family history of breast cancer He discusses his innovative work in FLASH radiotherapy, which aims to minimize side effects typically associated with traditional radiation, and his research on triple-negative breast cancer (TNBC), focusing on identifying subpopulations of TNBC stem cells through molecular profiling.
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    29 分
  • Adolescent Obesity and Bariatric Surgery with Dr. Janey Pratt

    Adolescent Obesity and Bariatric Surgery with Dr. Janey Pratt
    2025/09/02
    Clinical Professor Dr. Janey Pratt shares her passion for working with children and discusses the pressing issue of childhood obesity. As an adolescent bariatric surgeon, Dr. Pratt emphasizes that obesity is a disease. Although GLP1s — like Wegovy and Ozempic — offer some help, Dr. Pratt describes a multitude of evidence indicating surgery is a safe and more effective solution. In addition to surgery, Dr. Pratt also sheds light on Stanford’s comprehensive preoperative process for adolescent bariatric surgery, including necessary testing and evaluations to ensure patient safety as well as diet and exercise education for the whole family.
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    20 分
  • Empathy and Innovation in Microsurgery with Dr. Arash Momeni

    Empathy and Innovation in Microsurgery with Dr. Arash Momeni
    2025/08/01
    In this episode of Scrubcast, we sit down with Dr. Arash Momeni, an associate professor at Stanford University’s Department of Surgery, to discuss the latest advancements in reconstructive microsurgery. From his recent clinical trial—an anticoagulant head-to-head—to the integration of augmented reality (AR) technology in surgical practice, he is always looking for new ways to enhance precision, safety, and patient comfort. Dr. Momeni also provides a comprehensive overview of the emotional and logistical complexities faced by patients diagnosed with breast cancer, emphasizing the importance of empathy and education in the surgical process. Additionally, Dr. Momeni discusses his unique path to Stanford (completing residency TWICE) and his experiences with the American Society for Reconstructive Microsurgeons (ASRM) as the 2023 Godina Fellow and now Secretary. PRSJournal video: https://www.youtube.com/watch?v=GfLv2vogk5A Godina Lecture: https://www.youtube.com/watch?v=p_kPPUy7vLM Clinical Trial: https://pubmed.ncbi.nlm.nih.gov/40327806/
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    21 分