『Precision Medicine Saves Dollars & Makes Sense: How Population Health Screening Can Save Lives for Less』のカバーアート

Precision Medicine Saves Dollars & Makes Sense: How Population Health Screening Can Save Lives for Less

Precision Medicine Saves Dollars & Makes Sense: How Population Health Screening Can Save Lives for Less

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Where did you grow up and what attracted you to a career in medicine?

What is precision medicine?

This phrase has been used primarily to describe a different approach to cancer care.

  • tumor profiling – molecular characterization of a person’s cancer cells what drives it
  • but your POV is prevention, and implementing an pathway to integrate genetics and genomic information into the healthcare ecosystem to be acted upon at different points of care along a patient’s journey

When you started to build the program at The Christ Hospital in Cincinnati, how did you decide what you were going to go after? [HerCan testing + PGx]

  • early detection -- St I-II
  • prevention – prophylactic surgery
  • avoid side-effects or drug interactions [adverse events]

You must compete for resources. What motivated the hospital to want to invest in this kind of program which does not yield ROI immediately?

  • Was there pushback?
  • Who needs to champion this vision and work?

What were the results?

  • # patients tested
  • people in high-risk programs
  • money saved on unnecessary procedures or therapy

BOD of MADP Alliance for Disease Prevention-

Forgot to mention: MADP has rebranded from "Microbiome Alliance for Disease Prevention" to simply "MADP Alliance for Disease Prevention." Founders wanted to focus on Microbiome, but we've dramatically expanded scope :)

CDC Chronic Disease fast facts

Addressing Chronic Disease

Medicare—93% & Medicaid—82% in 2022 – chronic disease spending

People with chronic disease use a disproportionate share of health care resources

90% prescription drugs = $4.5 trillion

3-of-every 4 (75%) healthcare dollars spent on people with chronic conditions

  • Diabetes: ~$413 billion (2022) in medical costs and lost productivity.
    • 38M have diabetes + 98M pre-diabetes
    • CKD $96 billion
  • Heart Disease & Stroke $234 Billion/yr 🡺 $2 trillion by 2025
    • kills more American than anything (1-in-4 deaths)
    • HBP $79 billion

Employers loss of productivity – people w/top 10 chronic conditions absent/person ea yr = 164M work days lost = $184 billion in lost productivity

  • Depression – 25.6 days
  • Cancer 17 days
  • Respiratory – 15
  • Asthma – 12
  • Migraines – 11
  • Allergies – 8
  • Heart Disease – 6
  • Arthritis – 6
  • Diabetes – 2
  • HBP – 1

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