『Pickleball After Chemo: The Future of Cancer Treatment with Dr. Brandon Mancini | LMC #92』のカバーアート

Pickleball After Chemo: The Future of Cancer Treatment with Dr. Brandon Mancini | LMC #92

Pickleball After Chemo: The Future of Cancer Treatment with Dr. Brandon Mancini | LMC #92

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This episode is sponsored by NURP NURP helps busy physicians grow their wealth through AI-powered algorithmic trading designed for demanding careers. No day trading, no guesswork, and no constant market watching required. Ready to put your money to work? Visit start.nurp.com/doctors to learn more. Trading involves risk, and results may vary. This is not financial advice. —----------------------------- In this episode of Living with Metastatic Cancer, Dr. Peter Crane (physician and SFT patient) interviews Dr. Brandon Mancini. They cover Dr. Mancini’s journey from traditional radiation oncology to leading theranostics at Banff Health, the science behind molecularly targeted radiopharmaceuticals, current FDA-approved treatments, ongoing clinical trials, and how this field offers hope with highly precise, well-tolerated therapies. The conversation highlights opportunities for patients with rare and common cancers, practical access to treatments, and the rapid evolution of the field. Episode Highlights Dr. Mancini’s personal motivation: influenced by his mother’s breast cancer journey and her work as a clinical trials research nurse in radiation oncologyCareer pivot from community radiation oncology to subspecializing in theranostics after training in GermanyExplanation of theranostics: pairing diagnostic and therapeutic radiotracers that target specific proteins on or around tumor cellsFDA-approved treatments for metastatic prostate cancer (Pluvicto) and neuroendocrine tumorsExciting targets like FAP (fibroblast activation protein) for pan-cancer “basket” trials, including sarcomas and SFTCombination therapies, alpha vs. beta emitters, dosing/scheduling innovations, and moving treatments earlier in the disease courseBanff Health’s comprehensive program, clinical trials across ~15 tumor types, and serving patients from 26 states and 2 countriesPatient experience: minimal side effects allowing normal activities soon after treatmentFuture outlook: more approvals, earlier use, broader targets, and reduced reliance on traditional chemotherapy Top 3 Takeaways Theranostics represents a new era of precision medicine, highly targeted radiopharmaceuticals attack cancer at the molecular level while sparing healthy tissue, often with excellent tolerability.Patients with rare cancers like solitary fibrous tumors can benefit from emerging FAP-targeted trials and should explore clinical trial options and specialized centers.The field is advancing rapidly: centralized expertise, more trials, and earlier intervention are expanding access and improving outcomes across many tumor types. About Dr. Brandon Mancini Dr. Brandon Mancini is a radiation oncologist and Medical Director at Banff Health in Grand Rapids, Michigan, one of the world’s leading centers for theranostics. After a decade in traditional radiation oncology, he trained in Germany and helped launch Banff Health’s program in 2022. He specializes in targeted radiopharmaceutical therapies and is deeply involved in clinical trials expanding this field. Connect with Dr. Brandon Mancini Banff Health: banffhealth.com About the Host: Dr. Peter Crane is a board-certified physician, educator, and storyteller with a heart for service and a calling to spotlight doctors who make a difference—in their communities, in medicine, and in the lives they touch. Through Doctors Making a Difference, he brings you into intimate conversations with physicians who have overcome challenges, redefined success, and found purpose in and beyond the clinic. His goal is simple: to help more doctors stay in medicine by showing them what's possible. About the Show: Doctors Making a Difference is more than a podcast—it’s a movement to highlight the good, the gritty, and the deeply human side of medicine. In every episode, Dr. Peter Crane interviews physicians whose stories defy the script. From burnout recovery to bold career pivots, health challenges to quiet leadership, this show honors the truth that healing begins with connection—and doctors, too, deserve to be whole. Visit: doctorsmakingadifference.com LMC Series Note: Living with Metastatic Cancer (LMC) explores the science, decisions, and day-to-day realities of life with advanced disease—through candid physician–patient conversation The Doctors Making a Difference Podcast is for informational purposes only and does not substitute for medical, legal, or professional advice. Always consult appropriate experts regarding your unique circumstances. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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