Perimenopause, Gut Health & Stress: Nervous System Shift Women Don’t See Coming
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When you can understand the nervous system shift of perimenopause, you can improve sleep, mood, digestion, energy, and long-term resilience.
In this episode of The OWN IT Show, Justin Roethlingshoefer sits down with @CynthiaThurlow to break down why perimenopause is a “litmus test” for stress resilience, how the gut–brain axis and vagus nerve shape symptoms, and how to use data (like HRV) as communication, not obsession.
In this episode, you’ll learn:
✅ Why progesterone decline can drive anxiety, mood shifts, and sleep issues in perimenopause
✅ The gut–brain axis + vagus nerve connection (why “if your gut is off, your brain is off”)
✅ HRV as the language of stress (and how to interpret it without becoming performance-focused)
✅ Why trauma and stress history rewires the nervous system (and can impact midlife physiology)
✅ How to think about hormetic stressors (fasting, HIIT, cold exposure) so they don’t backfire
✅ Why midlife is meant to be a “pause”—boundaries, recovery, and lifestyle alignment
✅ Justin’s core thesis: health as worship and ownership, not biohacking as identity
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About Cynthia Thurlow, NP
Cynthia Thurlow is a nurse practitioner and women’s health educator focused on helping women thrive through perimenopause and menopause using science-backed, practical strategies. She is the author of:
📚 Intermittent Fasting Transformation
📘 The Menopause Gut: Balance Your Microbiome to Reclaim Your Health in Midlife and Beyond
➡︎ Cynthia’s website: https://www.cynthiathurlow.com/
➡︎ Follow Cynthia on Instagram: https://www.instagram.com/cynthia_thurlow_/
➡︎ The Menopause Gut (info / pre-order): https://www.penguinrandomhouse.com/books/777129/the-menopause-gut-by-cynthia-thurlow-np/
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