Haris was a friend and backing vocalist for Madonna and began working with Madonna in her Who's That Girl Tour. She appeared in the movie Truth or Dare, a documentary of backstage and onstage footage recorded during the Blond Ambition Tour. She also acted in the Madonna videos "Vogue" and "Music". With Donna DeLory, Haris participated in various Madonna tours including Who's That Girl Tour (1987), Blond Ambition Tour (1990), The Girlie Show Tour (1993) and The Drowned World Tour (2001).

During The Re-Invention Tour in 2004, Haris was replaced with Siedah Garrett. The official word from Haris is that she "would like to focus on her solo career and family." Haris was also absent from Madonna's following Confessions Tour, Sticky & Sweet Tour, MDNA Tour and Rebel Heart Tour.

Her vocal film work is also featured on the soundtracks of Corrina, Corrina, The Big Green, Noises Off, Coyote Ugly and Anastasia. She has also recorded television themes, including co-writing and performing two songs for the Fox series Dark Angel.

Haris toured with her father, until his death, while promoting their albums, Down Home Blues and In His Hands and Jazz Alley Cats.

Haris performed at benefits for AIDS, cancer research and Camp Harmony for inner city children. She is a supporter for the Music in the Classroom program and Rockers Against Drunk Driving and is an annual participant in the Season for Non Violence. Niki has made several television appearances in 2008 &...