Neuroscience Daily for 31 August follows 3 stories from r/neuro and r/neuroscience, moving through multiscale spatial transcriptomics resolves, geometric constraints cognitive inputs, psilocybin collapses visual change.

Chapters

• 00:00:00 — Intro
• 00:00:12 — Multiscale Spatial Transcriptomics Resolves
• 00:01:08 — Geometric Constraints Cognitive Inputs
• 00:02:18 — Psilocybin Collapses Visual Change
• 00:03:11 — Closing

1. Multiscale Spatial Transcriptomics Resolves

This bioRxiv preprint maps the cellular and molecular organization of the human amygdala using spatial transcriptomics. The researchers studied tissue from nine neurotypical donors and profiled more than 1.1 million cells across 13 spatial domains.

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2. Geometric Constraints Cognitive Inputs

This story from bioRxiv is about a preprint asking how fixed brain anatomy can support flexible thought. The researchers trained three types of recurrent neural networks on a working-memory task, gradually adding limits based on where signals could enter, leave, and connect in space.

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Reddit discussion

3. Psilocybin Collapses Visual Change

A new bioRxiv preprint examines how psilocybin changes visual change detection and cortical activity, with attention to somatostatin interneurons. The study reports that psilocybin sharply reduced the ability to detect visual changes.

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Reddit discussion

Episode closing.