In this episode, we explore groundbreaking research showing how Porphyromonas gingivalis, the bacterium behind gum disease, may be a key player in Alzheimer’s disease. Discover how oral bacteria can invade the brain, trigger inflammation, and accelerate memory loss — and how new small-molecule inhibitors may offer hope for future treatments targeting this powerful mouth–brain connection.

Stephen S. Dominy et al. Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.Sci. Adv.5,eaau3333(2019).

In this episode, we explore the powerful two-way relationship between diabetes and gum disease. Based on the 2013 Joint EFP/AAP Workshop consensus, Dr. Alexandre Ribeiro explains how periodontitis can worsen blood sugar control — and how diabetes, in turn, increases the risk and severity of periodontal inflammation. Discover why managing both conditions together is essential for better overall health.Chapple IL, et al. Diabetes and periodontal diseases: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Periodontol. 2013 Apr;84

In this episode, we explore how treating gum disease can do more than save your smile — it can help protect your heart. Discover how periodontitis affects endothelial function, the vital inner lining of blood vessels, and why inflammation in the mouth can lead to dysfunction in the arteries. We’ll discuss the latest research showing that periodontal treatment can improve vascular health and reduce cardiovascular risk. Join us as we connect oral health to overall wellness and uncover the science behind healing the heart through the gums.

Tonetti MS et al. Treatment of periodontitis and endothelial function. N Engl J Med. 2007;356:911–920.