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Mechanisms of Glaucomatous Damage

Mechanisms of Glaucomatous Damage

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Episode 43 – Mechanisms of Glaucomatous DamageWelcome back to Basic Sciences in Ophthalmology.

Hi, I am your host Dr Thomas Whitelaw and in this episode, we explore one of the most important and fascinating topics in ophthalmology: the mechanisms underlying glaucomatous optic neuropathy. Glaucoma is not simply a disease of raised intraocular pressure — it is a complex neurodegenerative disorder involving retinal ganglion cell death, axonal injury, vascular compromise, and biochemical stress.

Understanding the mechanisms of glaucomatous damage is essential for interpreting both clinical findings and modern therapeutic strategies.

Today’s episode is divided into three sections:


1. Axonal loss in glaucoma

2. Mechanical versus vascular theories

3. Neuroprotection strategies

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