『LEVELS – A Whole New Level』のカバーアート

LEVELS – A Whole New Level

LEVELS – A Whole New Level

著者： Levels
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Levels helps you understand your metabolic health with personalized data, expert guidance, and tools that connect your daily choices to measurable changes in your body. Our goal is to help you make better decisions about food, exercise, sleep, and long-term health. Connect with us: Become a Member: https://levels.link/wnl YouTube: https://youtube.com/@levels Instagram: https://instagram.com/levels Twitter: https://twitter.com/levels LinkedIn: https://linkedin.com/company/levels TikTok: https://tiktok.com/@levelsLevels 衛生・健康的な生活
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  • #301 - What Actually Moves the Needle on Cardiovascular Risk | Dr. Kevin Maki & Mike Haney

    #301 - What Actually Moves the Needle on Cardiovascular Risk | Dr. Kevin Maki & Mike Haney
    2026/06/18
    High cholesterol. Elevated ApoB. A positive CAC score. Now what?Most people quickly find themselves trapped between two extremes: simplistic advice to “cut saturated fat” and online influencers insisting cholesterol doesn’t matter at all.In this episode of A Whole New Level, Mike Haney sits down with clinical research scientist Dr. Kevin Maki to cut through the confusion.Drawing on more than 35 years of cardiovascular research, Maki explains why heart disease risk is about much more than LDL cholesterol alone. He breaks down the roles of inflammation, blood sugar, family history, kidney function, and lipoproteins, while also making a clear case for something many people resist: LDL and ApoB still matter. A lot.The evidence increasingly suggests that when it comes to atherosclerosis, lower for longer is better. That has important implications for diet, statins, and how early we should intervene.Mike and Dr. Maki also tackle saturated fat, seed oils, red meat, industry-funded research, and how to separate evidence from online nutrition debates.Free course: Improve your metabolic healthGet our free email course on how glucose, nutrition, exercise, sleep, and measurement can help you build habits that support better energy and long-term health: ⁠⁠⁠⁠https://levels.link/wnl⁠🎙️ About the Guest: Dr. Kevin Maki is founder and Chief Science Officer of Midwest Biomedical Research and an Adjunct Professor in the School of Public Health at Indiana University. A former president of the National Lipid Association, he has spent more than three decades designing and leading clinical trials focused on cardiovascular disease, diabetes, nutrition, and lipid management.His research has included studies on cholesterol-lowering therapies, dietary patterns, red meat, seed oils, inflammation, and cardiometabolic risk reduction.📍What Dr. Kevin Maki & Mike Haney discussed:0:00 — Dr. Maki’s background in clinical research4:30 — How industry-funded nutrition research actually works15:00 — The Framingham Heart Study and the “Big Four” risk factors20:00 — FLASH-GLICK: the ten factors that drive cardiovascular risk26:00 — Why inflammation may be the next frontier in prevention33:00 — LDL, ApoB, and the “lower for longer” principle42:00 — Particle size, ApoB, and what advanced lipid testing adds47:00 — Why everyone should know their Lp(a)51:00 — Saturated fat, seed oils, and the “compared to what?” problem62:00 — What the red meat evidence actually shows72:00 — Statins, lifestyle, and LDL treatment goals82:00 — Why earlier LDL lowering may provide the biggest benefit🔗 Helpful Links:Watch the conversation: https://youtu.be/l8QzuuTYxLIBeef Consumption and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials: https://pmc.ncbi.nlm.nih.gov/articles/PMC11621491/Low-Density Lipoprotein Cholesterol Lowering and Risk of Major Adverse Cardiovascular Events in Primary Prevention Trials: A Meta-Analysis: https://www.sciencedirect.com/science/article/pii/S1933287426000395PREDIMED Trial (Mediterranean Diet & Primary Prevention): https://www.nejm.org/doi/abs/10.1056/NEJMoa1200303CORDIOPREV Trial: https://pubmed.ncbi.nlm.nih.gov/35525255/The Framingham Heart Study: A Historical Perspective: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61752-3/abstractMidwest Biomedical Research: https://midwestbiomedicalresearch.com/National Lipid Association: https://www.lipid.org/✅ Subscribe here on YouTube: https://youtube.com/levelshealth?sub_confirmation=1👋 Who we are:Levels helps you understand your metabolic health with personalized data, expert guidance, and tools that connect your daily choices to measurable changes in your body. Our goal is to help you make better decisions about food, exercise, sleep, and long-term health.Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.
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    1 時間 19 分
  • #300 - Who Should Take GLP-1s? The Science of Obesity, Appetite & Weight Loss | Dr. Robert Kushner & Mike Haney

    #300 - Who Should Take GLP-1s? The Science of Obesity, Appetite & Weight Loss | Dr. Robert Kushner & Mike Haney
    2026/06/04
    What are GLP-1 drugs actually doing in the body, who are they for, and why might some people want to think twice before treating them like a six-month shortcut?For years, obesity treatment focused largely on behavior: eat less, move more, stay motivated. Yet many people lost weight only to regain it. According to obesity medicine pioneer Dr. Robert Kushner, that wasn’t a failure of willpower. It was a failure to fully understand the biology driving weight regulation.In this episode of A Whole New Level, Mike Haney sits down with Kushner, one of the leading figures in obesity medicine and a lead investigator on the landmark STEP trials, to discuss how GLP-1 medications are changing the field. He explains why these drugs may be the first treatments capable of helping patients “fight biology with biology,” why appetite regulation appears to work differently in different people, and why many patients describe a dramatic reduction in food noise after starting treatment.But this conversation goes beyond how the drugs work. Kushner also addresses one of the biggest questions facing obesity medicine today: who should actually take these medications? He explains why obesity specialists evaluate far more than a number on the scale, why someone hoping to lose a modest amount of weight may want to think carefully before pursuing treatment, and why successful long-term health still requires changes that no medication can provide.They also discuss obesity as a disease, the promise and limitations of telehealth prescribing, and why maintaining weight loss often requires something deeper than motivation: a shift in identity.Free course: Improve your metabolic healthGet our free email course on how glucose, nutrition, exercise, sleep, and measurement can help you build habits that support better energy and long-term health: ⁠⁠⁠https://levels.link/wnl⁠🎙️ About the Guest: Dr. Robert Kushner is Professor Emeritus of Medicine and Medical Education at Northwestern University Feinberg School of Medicine and one of the pioneers of modern obesity medicine. He is a past president of The Obesity Society, founder and former chair of the American Board of Obesity Medicine, and a lead investigator on the landmark STEP clinical trials that helped establish semaglutide as a treatment for obesity.📍What Dr. Robert Kushner & Mike Haney discussed:2:06 — Why obesity is more than willpower4:34 — The benefits and drawbacks of calling obesity a disease6:27 — Clinical vs. preclinical obesity17:36 — What obesity medicine misunderstood about weight regain18:44 — “Fight biology with biology”25:07 — Why weight maintenance is a different challenge than weight loss26:49 — The identity shift that helps people keep weight off27:52 — How GLP-1 drugs actually work31:09 — Why some people experience constant food noise34:09 — Why GLP-1s treat obesity but don’t cure it42:17 — The STEP and SELECT trials44:15 — Who should consider GLP-1 medications?45:44 — Why obesity treatment is more than an online prescription50:44 — What happens after you stop taking GLP-1s?🔗 Helpful Links:Watch the conversation: ⁠https://youtu.be/qdssFUAWVckDr. Robert Kushner: https://drrobertkushner.com/about/Northwestern Faculty Profile: https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=11686STEP Trial: https://www.nejm.org/doi/full/10.1056/NEJMoa2032183SELECT Trial: https://www.nejm.org/doi/full/10.1056/NEJMoa2307563👋 Who we are:Levels helps you understand your metabolic health with personalized data, expert guidance, and tools that connect your daily choices to measurable changes in your body. Our goal is to help you make better decisions about food, exercise, sleep, and long-term health.Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.
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    1 時間 14 分
  • #299 - Do Athletes Really Need More Carbs? | Dr. Andrew Koutnik & Mike Haney

    #299 - Do Athletes Really Need More Carbs? | Dr. Andrew Koutnik & Mike Haney
    2026/05/21

    Most athletes are told the same basic rule: the harder you train, the more carbs you need. But Dr. Andrew Koutnik argues the science is more complicated.


    In this episode, Mike Haney talks with Dr. Koutnik about how the body fuels exercise, why muscle glycogen may not explain “hitting the wall” as neatly as many people think, and why blood glucose, brain energy, insulin, and metabolic flexibility may matter more than conventional sports nutrition advice suggests.


    They discuss whether athletes really need 60, 90, or even 120 grams of carbs per hour, why some athletes may perform well on far less, and how to think about fueling as an individual experiment rather than a universal rule. Because apparently even “eat sugar while running” was too simple for human physiology to leave alone.


    Free course: Improve your metabolic health

    Get our free email course on how glucose, nutrition, exercise, sleep, and measurement can help you build habits that support better energy and long-term health: ⁠⁠https://levels.link/wnl⁠


    🎙️ About the Guest:

    Dr. Andrew Koutnik is a Visiting Research Scientist at the Florida Institute for Human and Machine Cognition, studying nutrition, metabolism, Type 1 diabetes, and human performance. He earned his PhD in medical sciences from the University of South Florida and has worked with groups including NASA and the Department of Defense.


    📍What Dr. Andrew Koutnik & Mike Haney discussed:

    • 00:42 Why carbs became central to sports nutrition
    • 05:30 How the body uses carbs, fat, ketones, and lactate for fuel
    • 13:45 Exercise, insulin sensitivity, and blood glucose
    • 21:20 Why muscle glycogen may not explain performance limits
    • 31:00 What “hitting the wall” may really mean
    • 39:15 The case for lower-carb fueling strategies
    • 48:30 Why more carbs don’t always mean better performance
    • 58:00 The problem with 90–120 grams of carbs per hour
    • 1:08:30 How athletes can test fueling for themselves
    • 1:17:00 What this means for everyday exercisers and marathoners


    🔗 Helpful Links:Watch the conversation: ⁠https://youtu.be/FfomxfyCchw

    Study discussed: Carbohydrate Ingestion on Exercise Metabolism and Physical Performancehttps://academic.oup.com/edrv/article/47/2/191/8432248Related paper: Substrate Oxidation Does Not Influence Middle Distance Running Performancehttps://www.mdpi.com/2072-6643/17/17/2771

    Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1


    📲 Connect:Connect with Dr. Andrew Koutnik: https://andrewkoutnik.com/X: https://x.com/AKoutnikInstagram: https://www.instagram.com/andrewkoutnikphd/Google Scholar: https://scholar.google.com/citations?hl=en&user=2BzUjqkAAAAJ


    👋 Who we are:

    Levels helps you understand your metabolic health with personalized data, expert guidance, and tools that connect your daily choices to measurable changes in your body. Our goal is to help you make better decisions about food, exercise, sleep, and long-term health.
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    1 時間 31 分
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