A new podcast, Killer Chemistry, explores how military science developed during the Manhattan Project became part of the biology of nearly every living thing on Earth.

Hosted by award-winning investigative journalist and author Callie Lyons, the series brings together scientific context, legal history, and lived experience to examine the origins and global presence of what are commonly referred to as “forever chemicals.”

Killer Chemistry is a true crime science podcast, presenting a complex and far-reaching story through a narrative format that is both accessible and deeply grounded in real-world events.

Author of the first book to chronicle forever chemicals and how the mysterious failure of an entire herd of cattle led to the discovery of global contamination, Lyons draws on years of research, firsthand experience, and ongoing dialogue with scientists and researchers to guide listeners through the story.

The series unfolds in easily digestible episodes, weaving scientific and legal concepts into a compelling narrative while offering practical insight listeners can apply within their own environments.

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Contact Killer Chemistry: killerchemistrypodcast@gmail.com

Support the show

You can support Killer Chemistry by following the show on the platform of your choice - doing so costs nothing and will give you a heads up when a new episode is released.

If you found this episode compelling, leave a rating or review. It helps others find the podcast. You can also find us on YouTube for additional content exploring high strangeness, UFO sightings in the valley, and much more.

The Killer Chemistry Podcast Companion, an adult coloring book, featuring artwork developed for the show, is available now on Amazon.

A man drives home on a cold November night in 1966, and the road in front of him stops feeling like the world he knows. Along Interstate 77 near Parkersburg, West Virginia, Woodrow Derenberger reports a craft close enough to halt traffic and a stranger with a fixed smile who “speaks” without moving his mouth. Minutes later it’s gone, but the details stick, especially that smile.

Ten days after, downriver near Point Pleasant and the abandoned TNT area, another report lands in the dark: something tall, winged, and watching, the sightings that will become the Mothman story. We trace how these encounters sit inside a larger Mid-Ohio Valley pattern, where UFO sightings cluster low to the ground along the Ohio River corridor and repeat across decades with the same shapes, the same movements, and the same silence. When investigators call a place like this a “window area,” they’re talking about persistence, not headlines.

Then we layer in the part we can measure. Chemical plants, power generation, industrial runoff, and forever chemicals like PFAS and PFOS have shaped this region for generations, with real consequences that show up in court records and health research tied to the C-8 class action lawsuit. We also walk through practical tools for documenting sightings, from writing down time and direction to searching the National UFO Reporting Center, and we dig into the FBI Vault under the Freedom of Information Act to see how “unidentified” gets filed, transferred, and often left unresolved.

If you’re drawn to true crime science, environmental contamination, Appalachian history, and high strangeness, come with us down the river. Subscribe, share the episode with a friend who loves mysteries, and leave a rating or review so more listeners can find Killer Chemistry.

Support the show

You can support Killer Chemistry by following the show on the platform of your choice - doing so costs nothing and will give you a heads up when a new episode is released.

If you found this episode compelling, leave a rating or review. It helps others find the podcast. You can also find us on YouTube for additional content exploring high strangeness, UFO sightings in the valley, and much more.

The Killer Chemistry Podcast Companion, an adult coloring book, featuring artwork developed for the show, is available now on Amazon.

Something moves at the edge of the headlights near Point Pleasant, West Virginia, and the witnesses can’t find words that fit. A huge shape. Red reflective eyes. The feeling of being watched. The story gets a name, The Mothman, and after the Silver Bridge collapses into the Ohio River, the legend locks into place as a “warning.” But I can’t stop thinking about a more unsettling possibility: what if the creature is a symptom of a landscape that was chemically changed long before anyone could measure it?

We trace the sightings back to the West Virginia Ordnance Works, a sprawling WWII TNT facility built in urgency and left with toxic waste, acid byproducts, and residual explosive compounds that didn’t stop moving when the machinery did. Industrial contamination doesn’t just sit politely in the past. It can leach into soil and groundwater, linger for decades, and shape how a community feels and functions years before any official recognition. We also connect that pattern to modern environmental health crises, including PFAS and PFOA forever chemicals, where the harm is invisible at first and the language arrives late.

Then we shift from story to action. A data center is proposed for land that has not been fully studied or remediated, and we lay out practical steps for tracking what’s coming: finding West Virginia DEP public notices, watching for air, water, and stormwater permits, using public comment periods to force real answers onto the record, and filing FOIA requests when the truth is buried in emails and internal reports. If you care about environmental justice, groundwater safety, and what gets built on top of wartime pollution, this is your roadmap.

Subscribe, share this with someone who loves true crime science and strange history, and leave a review with your take: was the Mothman a monster, a myth, or a signal?

Dedicated to Alex Cole - and the people of Mason County, West Virginia.

Support the show

You can support Killer Chemistry by following the show on the platform of your choice - doing so costs nothing and will give you a heads up when a new episode is released.

If you found this episode compelling, leave a rating or review. It helps others find the podcast. You can also find us on YouTube for additional content exploring high strangeness, UFO sightings in the valley, and much more.

The Killer Chemistry Podcast Companion, an adult coloring book, featuring artwork developed for the show, is available now on Amazon.