We close out our Mad Science series the only way we know how: with a very serious, deeply prestigious and completely unofficial Mad Science Film Awards.

After 58 films and more than a century of sci-fi cinema, we look back at the scientists, monsters, labs, experiments and terrible decisions that defined the season.

From Frankenstein, Dr. Jekyll and Mr. Hyde and The Invisible Man to The Fly, Re-Animator, Jurassic Park, Get Out and Poor Things, we trace how mad science evolved from gothic cautionary tales to atomic-age anxiety, body horror, corporate genetics, surveillance, consent and control.

Categories include Best Mad Scientist, Biggest Ego in a Lab Coat, Most Unethical Experiment, Best Creation, Best Lab, Hidden Gem and the big one: Best Mad Science Movie.

Plus we unveil what we will be covering the next series of Jounrey Through Sci-fi!

🚀 Join The JTSF Logbook
Recommendations, discoveries and updates from our journey through sci-fi cinema: journeythroughscifi.beehiiv.com

• Visit our website https://www.journeythroughscifi.com/
• Email Us!
• Support the podcast on PATREON
  
• Add us on INSTAGRAM
• Find us on TIKTOK
• Like us on FACEBOOK
• Follow us on LETTERBOXD

This week on Journey Through Sci-Fi, we head into the Star Trek universe to explore one of its most enduring mad science taboos: genetic engineering. From Space Seed and the rise of Khan to Enterprise's Augments arc and Deep Space Nine's shocking Bashir reveal, we trace how Star Trek keeps returning to the dangers of trying to "improve" humanity.

Along the way, we get into the Eugenics Wars, creator-creation relationships, scientific hubris, and why a utopian future still casts a long shadow over forbidden science.

Plus: Brent Spiner being superbly awful, Bashir's identity crisis, and why this theme runs through Star Trek for more than 200 years of in-universe history.

Episodes discussed:
Star Trek: The Original Series — "Space Seed" (S1E22)
Star Trek: Enterprise — "Borderland" (S4E04), "Cold Station 12" (S4E05), "The Augments" (S4E06)
Star Trek: Deep Space Nine — "Doctor Bashir, I Presume?" (S5E16)

Also referenced:
Star Trek — "What Are Little Girls Made Of?"
Star Trek: The Next Generation — "The Schizoid Man"
Star Trek: Voyager — "Tuvix"

What happens when one of sci-fi's oldest stories is reimagined for a modern audience?

In this episode of Journey Through Sci-Fi, we return to the origin of mad science — Mary Shelley's Frankenstein — through two new adaptations: Frankenstein (2025), directed by Guillermo del Toro, and The Bride! (2026), directed by Maggie Gyllenhaal.

This isn't just another adaptation.

It's a full-circle moment for the genre.

From the obsessive creator who dares to make life… to the creation who refuses to belong to him, these films show how the Frankenstein myth has evolved over 200 years of science fiction.

In this episode we explore:

• Why Frankenstein is still the blueprint for every mad scientist story
• How these new versions reinterpret the act of creating life
• What they keep — and what they completely reinvent — from the original myth
• Why The Bride! flips the perspective from creator to creation
• What this tells us about where sci-fi — and mad science — is heading next

From gothic horror roots to modern sci-fi storytelling, this is the evolution of one of the genre's defining ideas.

And a fitting end point for our Mad Science series.

Because sometimes the most important sci-fi story isn't about the future…

…it's the one we've been retelling all along.