This podcast by Associate Professor Yet Khor offers an update on interstitial pneumonia (IP) and interstitial lung disease (ILD), focusing on advancements in classification and diagnosis over the past two decades. Dr. Khor discusses the significance of recognizing both idiopathic and secondary causes, highlights key developments, such as the identification of idiopathic nonspecific interstitial pneumonia (NSIP), and advocates for improved diagnostic protocols, particularly concerning antigen-negative fibrotic hypersensitivity pneumonitis.

In a significant part of her discussion, Dr. Khor introduces the concept of disease behavior classification, which provides insights into patient prognosis and treatment goals. The lecture emphasizes the recognition of mixed presentations in patients, where they may exhibit features of multiple patterns rather than fitting neatly into a single classification. This highlights the complication of diagnosing ILD.

The podcast transitions into an exploration of recent findings related to the complications of diagnosing antigen-negative fibrotic hypersensitivity pneumonitis (HP), where a subset of patients exhibit progressive lung function decline despite the absence of identifiable antigens. Dr. Khor raises important considerations regarding the implications of these cases and the clinical challenges they pose, thus advocating for a re-evaluation of current diagnostic protocols and potential reclassification to spur further investigation in this area.

This podcast was recorded live at the Monash Lung and Sleep Institute: COPD, Interstitial lung diseases, upper airway pathologies and occupational lung diseases State of the Art Symposium in Melbourne.

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