In this episode of the Sunstone Health Podcast, we are joined by TMA Precision Health CEO Josh Resnikoff and the internationally recognized physician, engineer, and TMA Advisor Dr. Paul Carney for a conversation about confronting the systemic failures in rare disease diagnostics. Together, we explore the moral imperative behind TMA’s work, the crucial role of AI, and how combining elite clinical expertise with technology is reshaping the standard of care.

Dr. Carney shares his decades of experience on the clinical front lines, providing chilling examples of patients, from those with severe epilepsy to a child with brain leukemia, whose lives were severely impacted because vital diagnostic information was present but misinterpreted. He argues that traditional medical training is now obsolete for handling the 15,000+ known rare diseases, concluding that the 6 to 7 year diagnostic odyssey is due to systemic throughput failure. Josh connects this clinical struggle to his personal journey as a parent, explaining why building TMA became a moral crusade to ensure other families don't face the same emotional and financial uncertainty.

They reflect on the powerful and rare convergence of data and opportunity currently driving the field. Dr. Carney details how he acts as the "doctor in the box," viewing TMA's advanced AI and genetic data platform as the necessary extension of his clinical practice. This fusion allows TMA to handle the vast computational task of pattern recognition, freeing up human doctors to focus on judgment, empathy, and decision-making. The goal is to establish genetic testing as a routine front-line tool, bringing actionable precision medicine to scale.

This episode is an inspiring and deeply strategic look at the clinical urgency and engineering ingenuity behind TMA Precision Health, and the leaders working every day to bring clarity to families who have been searching for years.

Tune in to understand the strategic and ethical reasoning behind TMA’s mission to end the diagnostic odyssey.