GLP-1s like Ozempic (semaglutide) and Mounjaro (tirzepatide) are everywhere — but most people don’t understand what’s actually happening under the hood. In this episode, Jason and Lane break down the real conversation behind rapid weight loss, peptide safety, and how to avoid the hidden metabolic traps no one warns you about.

You’ll hear Jason explain why GLP-1s are powerful tools but not complete solutions, and Lane dives into what happens when appetite suppression leads to unintentional under-eating, hormonal shifts, and muscle wasting.

Together, they explore:

• What semaglutide and tirzepatide actually do to appetite, metabolism, and fat loss
• Why many people regain weight — and how to prevent it
• The muscle-loss problem nobody warns you about
• The essential role of protein intake, sleep, and strength training
• When to add supporting peptides for metabolism and muscle preservation
• How to know if you’re under-fueling and slowing your metabolic rate
• Why long-term success requires more than a GLP-1 shot

If you’ve ever wondered whether GLP-1 medications are enough on their own — or how to avoid the side effects while maximizing results — this episode is your roadmap.

In this episode, Jason and Lane do something they’ve never done before on the podcast.

They build a real, personalized peptide and bioregulator protocol — live and unfiltered.

After being taken out of his normal routines by dysautonomia and a reactivated Epstein-Barr virus, Lane opens up about what it’s like to live with persistent fatigue, immune dysregulation, and the emotional weight that comes with invisible illness. Despite years of experience in biohacking and health optimization, Lane found himself stuck in a cycle of hope, frustration, progress, and setbacks.

So instead of talking theory, Jason walks through how he would actually approach a case like this — step by step, calmly, and intentionally.

Together, they discuss

• Why inflammation, immune modulation, and mitochondrial support matter more than “one magic peptide”

• How to think about fatigue when the brain works but the body won’t cooperate

• The difference between thymus peptides, bioregulators, and immune signaling

• Why protocol timing, sequencing, and synergy matter more than stacking everything at once

• How to build a plan that supports the body instead of overwhelming it

You’ll hear Jason explain the reasoning behind each decision, not just what to use — including how to think about energy production, immune recovery, nervous system load, and long-term sustainability.

This episode is not about “copy this protocol.”

It’s about learning how protocols are built, how experienced practitioners reason through complex cases, and how to approach peptides with structure instead of randomness.

If you’ve ever felt overwhelmed by peptides, stuck in trial-and-error, or unsure how to rebuild your health after burnout, illness, mold, Lyme, long COVID, or immune challenges — this conversation will click.