『Innovate and React』のカバーアート

Innovate and React

Innovate and React

著者： Kevin Hares
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Talking to scientist about their innovations in chemistry 化学 科学
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  • Defying Markovnikov: A New Spin on the Wacker Oxidation

    Defying Markovnikov: A New Spin on the Wacker Oxidation
    2026/07/09
    In this episode of Innovate and React, I welcome back Thomas Bouveyron from and TH Köln to explore how we can make conventional petrochemical pathways more sustainable. We look into the synthesis of n-decanal, which is a crucial molecule in the fragrance industry and a key scent in Chanel No. 5. Thomas' gaol is to shift from crude oil- to bio-based building blocks. How do you bend the rules of classical Wacker oxidation to favor the usually unfavored anti-Markovnikov product? Thomas shares his methodology, combining statistical Design of Experiments (DOE) and computational Density Functional Theory (DFT) calculations to unravel more of the catalytic mechanism. We also discuss the practical engineering hurdles of catalyst fatigue, solvent participation, and the tricky business of separating decanal from decanone.
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    41 分
  • The Perfect Compromise: Unlocking the Future of Green Hydrogen with AEM

    The Perfect Compromise: Unlocking the Future of Green Hydrogen with AEM
    2026/06/15
    In this episode of Innovate and React, I met with Miriam Hesse and Bastian Kaufmann, researchers at the Hydrogen and Fuel Cell Center (ZBT) to discuss the rising potential of Anion Exchange Membrane (AEM) water electrolysis. We explore how AEM serves as the perfect compromise between traditional alkaline systems and proton exchange membrane (PEM) electrolysis, offering high efficiency without the reliance on expensive precious metals like platinum and iridium. Miriam and Bastian share their journey into hydrogen research and how ZBT acts as a crucial bridge between fundamental chemistry and applied industrial engineering across the entire hydrogen value chain. The conversation dives deep into the specific challenges and innovations within AEM technology, from navigating the historical bottlenecks of polymer membrane stability to the intricate process of fabricating homogeneous catalyst layers directly onto porous transport layers (PTLs). We discuss the promising use of nickel-based catalysts to optimize the oxygen and hydrogen evolution reactions. Furthermore, we examine the complexities of scaling this technology for industry, emphasizing the need for long-term degradation data, accelerated stress tests, and advanced analytical methods like electrochemical impedance spectroscopy (EIS) and the distribution of relaxation times (DRT) to pinpoint exactly where performance losses occur in real-world systems.
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    56 分
  • Stopping PFAS at the Source: Innovating Industrial Wastewater Treatment

    Stopping PFAS at the Source: Innovating Industrial Wastewater Treatment
    2026/05/22
    In this episode of Innovate and React, I met with Dr. Rhea Machado, the CEO and co-founder of Porelio, to discuss their solution for removing forever chemicals from our drinking water. We explore the widespread issue of PFAS accumulating in our water, our food, and even unborn children, and how short-chain PFAS remain a massive challenge because traditional methods like activated carbon and ion exchange resins fail to capture them. Rhea shares Porelio's journey as a spinoff from the Technical University Berlin, where they took highly efficient but traditionally hard-to-produce functionalized ordered meso-porous silica and successfully scaled it for industrial use. The conversation dives deep into Porelio's innovative approach, which uses an ordered pore structure equipped with engineered functional groups to quickly and selectively catch specific target molecules, whether that is toxic PFAS in industrial wastewater or valuable precious metals. We discuss the multifaceted challenges of scaling a B2B chemistry startup, from defining unit economics to simultaneously scaling production and navigating regulatory pathways like REACH, all while trying to find innovative R&D partners in a conservative industry.
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    28 分
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