『CRITKNOW』のカバーアート

CRITKNOW

CRITKNOW

著者: Bharath Kumar Tirupakuzhi Vijayaraghavan
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Our take on the latest critical care evidence with deep insights on methods, interpretation, clinical relevance and so much more!

CRITKNOW is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman.

Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf

Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapy. A highly respected teacher and educator, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: https://icuconsultants.com/dr-ramesh-venkataraman/

Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (https://icuconsultants.com/). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar)

Views expressed are personal.

2026 Bharath Kumar Tirupakuzhi Vijayaraghavan
エピソード
  • Middle Meningeal Artery Embolization for Chronic SDH: STEM trial
    2026/09/01

    In this episode, we review the evidence on middle meningeal artery embolization for chronic subdural hematoma, with a deep dive into the STEM trial and a brief overview of other key studies. Alongside a critical appraisal of the clinical trials, we also include a short methods segment on stratification in the context of randomization.

    Our podcast is available on Apple, Spotify, and YouTube. If you are listening on Apple or Spotify, please note that the YouTube version includes images and text overlays that may further aid understanding of the trials discussed.

    If you have been enjoying our content, please like, comment, subscribe, and share!

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    31 分
  • LOGICAL
    2026/08/08

    In this episode, we review the LOGICAL trial, which compared conservative versus liberal oxygenation targets in patients admitted to the ICU following cardiac arrest. We discuss the underlying rationale, summarize prior evidence, and examine the trial in detail. We also include a methods segment on response-adaptive randomization, before concluding with a discussion of the study’s strengths and limitations.

    Our podcast is available on Apple, Spotify, and YouTube.

    If you enjoy our content, please like, comment, and subscribe—it really helps us reach a wider audience. Thank you!

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    38 分
  • SODa-BIC
    2026/07/09

    In this episode, we break down the recently published SODa-BIC trial, exploring the role of IV sodium bicarbonate in critically ill patients with metabolic acidemia. We walk through the rationale, prior evidence, PICO, results, and our key critiques and takeaways. We also include a short methods segment on adaptive sample size re-estimation.

    You can also find us on Apple Podcasts and Spotify.

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    41 分
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