If you are currently taking a GLP-1 like Semaglutide or Tirzepatide and concerned about gaining weight after discontinuing — then this episode is for you. Gaining fat is a real issue.

In this episode of The Medical Weight Loss Show, Dr. Andrea Walker, DNP, FNP-C—owner of Serenity Health & Wellness—breaks down the growing discussion highlighted in recent media coverage about “yo-yo” weight gain after stopping GLP-1 medications.

Many patients will experience weight regain—but what’s most concerning isn’t just the number on the scale. It’s how the body regains weight, often favoring fat over muscle, and what that means for long-term metabolic health.

Dr. Walker explains:
• Why appetite and hunger hormones rebound after stopping GLP-1s
• The science behind metabolic adaptation and weight regain
• How muscle loss during weight loss impacts body composition
• Why repeated weight cycling can worsen metabolic health
• The importance of strength training, protein intake, and maintenance planning
• How to create a sustainable, long-term weight loss strategy

This episode is a must-listen for anyone currently on GLP-1 medications, considering them, or struggling to maintain weight loss.

Because real success isn’t just losing weight—it’s keeping it off.