How accurate are the tests we rely on to diagnose IgE-mediated food allergy? In this episode, we explore the science behind skin prick testing, serum-specific IgE, and oral food challenges, examining their sensitivity, specificity, predictive values, and real-world limitations.

Join us as we separate evidence from assumption, discussing false positives, cross-reactivity, and component-resolved diagnostics—and how to interpret results in the context of clinical history.

Whether you’re a clinician, allergy trainee, or researcher, this episode will help you navigate the complex landscape of allergy diagnostics with clarity and confidence.

Source:

• Riggioni, C., Ricci, C., Moya, B., Wong, D., van Goor, E., Bartha, I., Buyuktiryaki, B., Giovannini, M., Jayasinghe, S., Jaumdally, H., Marques-Mejias, A., Piletta-Zanin, A., Berbenyuk, A., Andreeva, M., Levina, D., Iakovleva, E., Roberts, G., Chu, D., Peters, R., du Toit, G., Skypala, I. and Santos, A.F. (2024) 'Systematic review and meta- analyses on the accuracy of diagnostic tests for IgE- mediated food allergy', Allergy, 79, pp. 324-352. DOI: 10.1111/all.15939.

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