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  • #52 - Beyond the Algorithm: Measuring AI Confidence in Biomanufacturing

    #52 - Beyond the Algorithm: Measuring AI Confidence in Biomanufacturing
    2026/01/13
    🎙️ Masaki Yamada — Head of Product at Invert, helping biomanufacturing teams quantify trust in AI.👩‍🔬 Hosts: Sura Hadi & Mike Ouren🎧 Episode Title:“Beyond the Algorithm: Measuring AI Confidence in Biomanufacturing”Hallucinations, trust, and the space between - that’s where the future of science is being written.From NASA’s microbial fuel cells to AI-native bioprocessing, Masaki Yamada joins us to unpack how Invert is helping scientists measure something once thought unquantifiable: confidence in AI.This episode dives deep into the evolving relationship between humans and algorithms in the biomanufacturing world — exploring trust, reproducibility, and what it means to build a digital scientist that actually knows when it’s wrong.🎯 What You’ll LearnWhy “hallucinations” in AI aren’t always bad — and when they definitely are.How Invert uses evals to measure model reliability in real-world biotech settings.The difference between objective vs. subjective AI benchmarking.How digital transformation is really going inside major biopharma labs.What the “AI-native scientist” of the future looks like.💡 Picks of the Week📚 Masaki Yamada – The Stormlight Archive by Brandon Sanderson🧰 Mike Ouren – The MagSafe Grip & “The Ticket” Seatbelt Gadget🧠 Sura Hadi – KDP self-publishing exploration for indie creators👇 What’s the right balance between creativity and control when it comes to AI in science? Drop your thoughts in the comments — we’ll feature the best takes next episode.🎬 Chapters00:00 – Cold Open00:15 – Welcome to the AI Thought Leaders Series01:00 – The Hallucination Debate: Creativity vs. Accuracy03:16 – What “Trust” Means in Biomanufacturing07:16 – Defining Confidence in AI Outputs10:06 – Human Benchmarking & Evals11:34 – NASA Origins: From Space Fuel Cells to Biotech15:04 – Inside Invert: Structuring Data for Transparency19:44 – From Paper to Platform: Digital Transformation Realities24:21 – Are Labs Really Digitized?25:46 – Adoption, Resistance & Culture Change27:55 – Security, IP & Data Trust28:28 – Designing the Future: People-in-the-Loop Automation33:05 – Digital Cognition: The Next Phase of AI Integration37:51 – The AI-Native Scientist40:01 – Picks of the Week46:56 – Wrap-Up🔔 Subscribe to Helical BrewWe explore the intersection of AI, automation, and the future of science.Subscribe & never miss an episode → / @helicalbrew 📩 Want to promote or be a guest? Email us: helicalbrew@gmail.com📍 TikTok, Shorts & more: @helicalbrew📌 SHORTS (Quick Clips from the Episode)▶️ • “Hallucinations, On Purpose?” #helicalbrew... ▶️ • Measure Trust, Not Hype #helicalbrew #vira... #HelicalBrew #AIThoughtLeaders #LabAutomation #BiotechInnovation #SciencePodcast #AIinScience #AIinBiotech #Biomanufacturing #MachineLearning #DigitalTransformation #Invert #DataIntegrity #Reproducibility #AutomationInBiotech #FutureOfScience #PodcastShorts #ScienceAndTech
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    48 分
  • #51 - Dogs, Planes & Pizza Slices – Helical Brew Goes Off-Script

    #51 - Dogs, Planes & Pizza Slices – Helical Brew Goes Off-Script
    2025/11/11
    Hosts: Sura Hadi & Mike OurenSeries: Unfiltered Brew – Helical Brew PodcastBold summary:After a few weeks abroad, Mike’s back — jetlagged, caffeinated, and ready to unpack everything from the Munich SLAS meetup to airplane fuel stats, Aurora Borealis sightings, and why Sura’s dog might just be her emotional support animal.It’s an unfiltered catch-up episode filled with travel stories, food debates, and the kind of chaos only Helical Brew can deliver.🎙 Highlights:Aurora Borealis at 38,000 feet 🌌Dark vs Milk Chocolate showdown 🍫-Why Detroit pizza deserves more respect 🍕Emotional support dogs & airline rants ✈️Gaming talk & what’s next for Helical Brew 🎮👋 Join the conversation:Comment below with your travel pet stories — or your most controversial pizza opinion.📌 Subscribe for weekly episodes → / @helicalbrew 📩 Want to promote or be a guest? Email us: helicalbrew@gmail.com📍 TikTok, Shorts & more: @helicalbrew⏱️ EPISODE CHAPTERS – NAVIGATE THE EPISODE0:00 Cold Open – Emotional Support Animal 🐾0:06 Welcome to the Unfiltered Brew0:40 Aurora at 38,000 ft2:28 iPhone vs Android4:22 Chocolate Debate5:46 Pizza & Craft Beer6:54 Turbo Talk & Cars8:56 Airlines: Southwest vs Emirates11:38 Favorite Cuisines12:43 Street Food Around the World14:11 Walmart Adventures15:57 Dogs or Cats?17:02 Airline Policies & Fairness18:16 Gaming Showdown20:34 Stream Plans & Outro📌 SHORTS (Quick Clips from the Episode)▶️ • Milk vs Dark Chocolate 🍫 — Why Europe Wins... ▶️ • Seat-Saving 101 (Do Not Try This 😇) #viral... #HelicalBrew #UnfilteredBrew #PodcastClips #SciComm #AutomationLife #TravelStories #DogEdition #PizzaDebate #SLAS2025 #PodcastReel #ViralPodcast #ScienceCulture #Biotech #SciencePodcast #PodcastShorts #ScienceAndTech #ViralShortsVideo #ViralReels #PodcastClips #warzone #viralshortsvideo #viralreels #viralvideos #viral_video #viralshorts #science #podcast
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    24 分
  • #50 - ISPE Boston at Gillette Stadium –Robots, Enclosures & Boston Energy

    #50 - ISPE Boston at Gillette Stadium –Robots, Enclosures & Boston Energy
    2025/11/11
    🎙️ Hosts: Sura Hadi, Mike Ouren🎧 Episode Title: ISPE Boston at Gillette Stadium – Robots, Enclosures & Boston EnergyFrom Rockwell rails to Germfree enclosures (and a field-goal after-party), Sura and Mike unpack what went down at ISPE Boston 2025 — hosted inside Gillette Stadium.This Helical Brew episode brings the perfect mix of automation insights, event chaos, and Boston flavor.🔍 We cover:• ISPE Boston recap from the field-level after-party 🏟️• Vendor tech that mattered: Rockwell MagneMotion, Germfree enclosures & 3D motion pucks• When not to bring a robot arm - reading the room at vendor shows• Zdeno Chara’s surprise appearance 👀• Pick of the Week: Orchard Skate Shop deck (Castle Island Brewery collab)• GORUCK gear + road-warrior travel talk💡 If you’ve ever packed for a conference, debated bringing a demo robot, or tried to kick a field goal in dress shoes - this one’s for you.📌 Subscribe for weekly episodes → / @helicalbrew 📩 Want to promote or be a guest? Email us: helicalbrew@gmail.com📍 TikTok, Shorts & more: @helicalbrew⏱️ EPISODE CHAPTERS – NAVIGATE THE EPISODE00:00 Cold Open – After-party field goals00:19 Welcome back! Travel & time zones01:00 E Tech podcast & LAIR lair04:19 ISPE Boston @ Gillette Stadium05:19 Zdeno Chara cameo09:46 Vendor tech: Siemens, Rockwell & Germfree12:31 Enclosure math & integration talk15:41 Why we didn’t bring a robot arm16:43 Picks of the Week – Orchard deck & GORUCK shoes27:11 Tunnel prank in Boston30:39 Boston culture & seafood stories32:44 Outro – Wrap up & subscribe🔗 Mentions & Shoutouts🌐 ISPE Boston: https://ispeboston.org🌐 Rockwell MagneMotion: https://www.rockwellautomation.com🌐 Germfree Enclosures: https://www.germfree.com🌐 Orchard Skate Shop: https://orchardshop.com📌 SHORTS (Quick Clips from the Episode)▶️ Boston Tunnel Prank → • 🚗 “Boston’s Underwater Tunnel Prank?! 😂 | ... ▶️ ISPE @ Gillette Stadium Reveal → • 🏟️ “Wait… ISPE Boston Was at GILLETTE STAD... #HelicalBrew #ISPEBoston #GilletteStadium #LabAutomation #IndustrialRobotics #LifeSciences #Automation #EngineeringHumor #WomenInSTEM #SciencePodcast #TechCulture #PodcastShorts #AutomationInnovation #ViralShorts #ScienceAndTech
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    34 分
  • #49 - Class Rings, Metric Fails & Why Women’s Pockets Suck

    #49 - Class Rings, Metric Fails & Why Women’s Pockets Suck
    2025/11/08

    🎙️ Hosts: Sura Hadi, Mike Ouren, Elizabeth Rodziewicz

    🎧 Episode Title: Unfiltered Brew - Class Rings, Metric Fails & Why Women’s Pockets Still Suck

    From class rings and college debt to metric vs. imperial hardware fails, McMaster wins, and a Theranos throwback — this Unfiltered Brew episode is all chaos, caffeine, and comedy. We even end with the rant of 2025: women’s pockets.

    🔍 We cover:

    • College rings, EU free tuition, and student debt

    • Metric vs. imperial IRL — Lowe’s fail → McMaster saves the day

    • Space program sidebar: when NASA mixed units

    • Theranos mini-lab slides (“images not to scale”)

    • ISPE Boston shoutout + road time updates

    • Ferrari fandom, Le Mans flips & streaming fatigue

    • Phone fails and the ultimate rant: women’s pockets in 2025

    💡 If you’ve ever fought with hardware store parts, side-eyed Theranos, or cursed fake jacket pockets — this one’s for you.

    📌 Subscribe for weekly episodes → https://www.youtube.com/@HelicalBrew?sub_confirmation=1

    📩 Want to promote or be a guest? Email us: helicalbrew@gmail.com

    📍 TikTok, Shorts & more: @helicalbrew

    ⏱️ EPISODE CHAPTERS – NAVIGATE THE EPISODE

    00:00 Cold Open – Warzone banter + class ring

    01:07 Metric vs. Imperial IRL02:11 McMaster saves the day

    04:49 Space program sidebar → Theranos flashback

    07:24 ISPE Boston + Road time

    08:11 Ferrari, Formula 1 & Le Mans

    09:03 Streaming wars & Schitt’s Creek

    12:01 Phone fails → Women’s pockets rant

    14:14 Outro – Wrap up & socials

    🔗 Mentions & Shoutouts

    🌐 ISPE Boston: https://ispeboston.org

    🌐 McMaster-Carr: https://www.mcmaster.com

    📌 SHORTS (Quick Clips from the Episode)

    ▶️ McMaster Saves the Day → https://youtube.com/shorts/mRCtFj_LYe8?feature=share

    ▶️ Women’s Pockets in 2025 → https://youtube.com/shorts/DYhNMGHF03o?feature=share

    #HelicalBrew #UnfilteredBrew #LabLife #EngineeringHumor #McMaster #Theranos #Biotech #SciencePodcast #PodcastShorts #ScienceAndTech #ViralShortsVideo #ViralReels #PodcastClips #warzone #viralshortsvideo #viralreels #viralvideos #viral_video #viralshorts #science #podcast
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    15 分
  • #48 - The 2025 Hiring Curve (Part 2)

    #48 - The 2025 Hiring Curve (Part 2)
    2025/11/07

    🎙️ Hosts: Mike Ouren, Sura Hadi, Elizabeth Rodziewicz

    🎧 Episode Title: The 2025 Hiring Curve: Biotech, Automation & What’s Next (Part 2)

    Ghosting. Bottlenecks. Myths about hiring made easy.

    In Part 2 of our Science Means Business conversation with Ian Cooper and Chris Gaetani of BioMed Recruitment, we dig into the hard truths shaping biotech and automation jobs in 2025.

    🔍 We cover:• Ghosting & bottlenecks in the hiring process• How recruiters can (and should) give feedback

    • Strategies for candidates stuck in a stalled job search• The myth of “easy hiring” in a talent-rich market

    • Why hiring managers need partners, not more resumes

    • Networking, adaptability, and building pipelines without burnout

    • Picks of the Week: tools, tea, travel pillows & more

    💡 If you’re hiring in biotech or automation - or job hunting in 2025 - this one’s packed with real talk.

    📌 Subscribe for weekly episodes → https://www.youtube.com/@HelicalBrew?sub_confirmation=1

    📩 Want to promote or be a guest? Email us: helicalbrew@gmail.com

    📍 TikTok, Shorts & more: @helicalbrew

    ⏱️ EPISODE CHAPTERS – NAVIGATE THE EPISODE

    00:00 Cold Open - Cane’s Tea vs Cane’s Sauce?

    00:42 Intro & Recap of Part 1

    02:05 Ghosting & Bottlenecks Era

    07:18 Why Feedback Matters

    10:16 Stalled Job Searches & What to Do

    15:29 Adaptability & Startups

    19:34 Networking Events (LRIG, Lab Automators, Europe)

    27:10 Hiring Managers: What to Stop Doing

    34:39 Recruiters as Partners, Not Vendors

    41:17 Busting Hiring Myths in Biotech

    47:01 Picks of the Week (Tools, Tea & Travel Pillows)

    55:00 Wrap Up & Outro

    🔗 Guest & Company Links:

    🌐 BioMed Recruitment: https://biomedrecruitment.com

    👤 Ian Cooper on LinkedIn: https://www.linkedin.com/in/ian-cooper17/

    👤 Chris Gaetani on LinkedIn: https://www.linkedin.com/in/chris-gaetani-586a3a129/

    📌 SHORTS (Quick Clips from the Episode)

    ▶️ https://youtube.com/shorts/uZr2aOYDK_Y?si=owT4o5jjG4m0ljNc

    ▶️ https://youtube.com/shorts/rjh-qfQUy4k?si=h2NOMZwmJTlfwIN9

    #HelicalBrew #ScienceMeansBusiness #BiotechJobs #HiringTrends #LabAutomation #Ghosting #RecruitingTips #AutomationCareers #BiotechHiring #BioMedRecruiting #JobSearch2025 #CareerPivot #SciencePodcast #AutomationInBiotech #FutureOfWork #BiotechCareers #ViralShortsVideo #ViralReels #PodcastClips #PodcastShorts
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    58 分
  • #47 - The 2025 Hiring Curve (Part 1)

    #47 - The 2025 Hiring Curve (Part 1)
    2025/09/13
    🎙️ Hosts: Mike Ouren, Sura Hadi🎧 Episode Title: The 2025 Hiring Curve: Biotech, Automation & What’s Next (Part 1)What’s changed in biotech hiring since January? What hasn’t? And what’s next for lab automation jobs in 2025?In this exclusive two-part episode of Science Means Business, Sura and Mike sit down with Ian Cooper & Chris Gaetani of BioMed Recruitment for a mid-year hiring check-in that every candidate and hiring manager should hear.This week in Part 1, we cover:💻 Why resumes are fading and video intros are winning candidates jobs💸 The “compensation hangover” from post-COVID salary spikes📊 Which biotech and automation roles are hardest (and easiest) to fill🏢 The surprising stat: 37% of SLAS companies are still hiring in the U.S.👉 And we leave you on a cliffhanger: Chris’s Hot or Not trend picks, coming in Part 2.If you’re navigating the biotech job market, hiring for automation talent, or just curious how careers are shifting in 2025 — this episode is for you.🎧 Subscribe for new episodes weekly → / @helicalbrew 📩 Want to be promoted or be a guest? Email us: helicalbrew@gmail.com📍 TikTok, Shorts & more: @helicalbrew⏱️ EPISODE CHAPTERS – NAVIGATE THE CONVERSATION00:00 Cold Open (Rotary Phone Bit)00:32 Host Intro: Welcome to Science Means Business01:00 Guest Intros: Ian & Chris from BioMed Recruiting02:00 Icebreaker: Resume & Job Trends That Made Us Shake Our Heads05:30 Video Intros vs Resumes: Why Candidates Stand Out on Camera08:00 The Compensation Hangover: Resetting Expectations in 202513:00 Harder vs Easier Roles to Fill in Lab Automation17:00 SLAS Stat: 37% of Companies Still Hiring20:00 Setting the Stage: Chris’s Hot or Not (to be continued in Part 2)🔗 Guest & Company Links:🌐 BioMed Recruitment: https://www.biomedrecruitment.com/👤 Ian Cooper on LinkedIn: / ian-cooper17 👤 Chris Gaetani on LinkedIn: / chris-gaetani-586a3a129 📌 SHORTS (Grab Quick Highlights)▶️ Video Intros vs Resumes: • 📹 Why video intros beat resumes in biotech... ▶️ Compensation Hangover: • 💸 The Post-COVID Compensation Hangover in ... #HelicalBrew #ScienceMeansBusiness #BiotechJobs #HiringTrends #Compensation #Recruiting #BioMedRecruiting #LabAutomation #BiotechCareers #Hiring2025 #CareerPivot #FutureOfWork #SciencePodcast #AutomationInBiotech #BiotechInnovation #ScienceAndTech #viralshortsvideo #viralreels #viralvideos #labautomation #biotech
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    29 分
  • #46 - Red Chair, Closet Beer, #peloton Fame & #frenchie Drama #helicalbrew #viral #shortvideo

    #46 - Red Chair, Closet Beer, #peloton Fame & #frenchie Drama #helicalbrew #viral #shortvideo
    2025/09/04
    🎙️ Hosts: Mike Ouren, Sura Hadi, Elizabeth Rodziewicz🎧 Episode Title: Red Chair, Closet Beer, Peloton Fame & Frenchie DramaRed chair returns. Closet beer gets cancelled. Peloton price therapy, Frenchie recovery, and a lab-events blitz.This week on Helical Brew: Unfiltered Brew (Ep. 46), Sura, Mike, and Elizabeth go full cozy chaos:🔴 Red-on-red & the chair that wants a mic🍺 Closet beer confessions (and why IPAs have a clock)🚴 Cody Rigsby shout-outs, OG vs. new Peloton, and price reality🐶 Hyper-Frenchie surgery recovery + crate-scream saga🎛 Stream decks, soundboards, and the “we need an intern” moment🧭 LRIG / SLAS / Oxford Global / Biocom event rundown🥾 Rucking, TRX, & parenting-by-embarrassment🎁 Picks of the Week: bamboo stand, GORUCK patches, “presence”If you’re into biotech banter, Peloton chaos, closet beer debates, or just need a laugh after a long week - you’re in the right place.🎧 Subscribe for new episodes weekly → / @helicalbrew 📩 Want to be promote or be a guest? Email us: helicalbrew@gmail.com📍 TikTok, Shorts & more: @helicalbrew⏱️ EPISODE CHAPTERS – NAVIGATE THE CHAOS00:00 The red chair takes the spotlight01:15 Summer vanishes + e-bike mania (and mishaps)02:49 Peloton speed runs & Cody Rigsby hype03:40 Quarantine Peloton: regrets, price drops & OG bike woes05:30 “At that price, the coach better be included”06:27 Producer shout-outs & shorts grind07:43 ISPE San Diego recap + live-show banter08:32 Mira Mesa eats & Somi Somi dessert detour09:29 Parenting by embarrassment (feat. Nutella vs custard)10:22 Frenchie surgery, sedation, & crate-scream saga12:39 Townhouse perks: unexpected quiet14:29 Stream decks, gamer rigs & overkill setups17:13 Streaming dreams & “we need an intern” callout18:05 Upcoming events: LRIG, Niklas Forum, MSACL, ILMAC, SLAS21:14 NYC LRIG crossover & Canada socials brewing23:35 Oxford Global + Biocom previews24:35 SLAS lead-up teasers & guest hints25:59 Happy hours & meetups (Reno → London → Munich)27:31 Picks of the Week: bamboo stand, GORUCK challenge, digital presence29:11 TRX workouts, rucking & the hashtag challenge32:12 Parenting vs. rucking (a heavy load)33:30 “Did you miss us?” banter returns35:08 Wrap-up + subscribe call📌 SHORTS (Quick Clips from the Episode) ▶️ • 🍺 Stop Hoarding Old Beer | #helicalbrew E... ▶️ • Peloton Fame = Cody Rigsby Shout-Out #heli... #HelicalBrew #UnfilteredBrew #Podcast #Peloton #ClosetBeer #FrenchieDrama #BiotechLife #LabAutomation #SLAS #LRIG #BeerTalk #Parenting #Rucking #TRX #SciencePodcast #ComedyPodcast #BiotechEvents #viralshortsvideo #viralreels #viralvideos #viral_video #labautomation #biotech #biotechstartups #biotechinnovation #biotechnology #science #sciencepodcast #scienceandtech #podcastclips #podcastshorts
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    37 分
  • #45 - Cristian Ponce on Robots, AI Engineers & the Cloud Lab Revolution

    #45 - Cristian Ponce on Robots, AI Engineers & the Cloud Lab Revolution
    2025/08/26
    🎙 Episode 45 – Cristian Ponce | CEO & Co-Founder – Tetsuwan Scientific"Interfacing with the Future: Why Lab Robots Still Don’t Understand Scientists"What’s really broken in lab automation? According to Cristian Ponce, it’s not the hardware—it’s the human interface.In this episode of our AI Thought Leaders series, we sit down with Cristian, a Caltech-trained bioengineer and co-founder of Tetsuwan Scientific, to dive into the real reason most lab robots fail to deliver—and what it will take to build a fully autonomous, cloud-based laboratory future.🔍 We cover:• Why lab automation still feels clunky (hint: it's not the pipettes)• How AI can act as a translator between scientists and machines• Dead volume wars, snap cap disasters, and the cost of bad UX• What “automated automation engineering” really means• The bold idea of a robot-powered lab that lives in the cloud• Why storytelling and systems-thinking matter in biotech entrepreneurship• How Tetsuwan is stewarding a new, forest-minded future for lab automation☁️ From Eroom’s Law to Astro Boy, from dead volume to dead dreams of automation—this one goes deep.📌 Subscribe for more bold ideas in AI, lab automation, and biotech: / @helicalbrew 📩 Want to be promote or be a guest? Email us: helicalbrew@gmail.com📍 TikTok, Shorts & more: @helicalbrew⏱️ EPISODE CHAPTERS – NAVIGATE THE EPISODE00:00 – Intro01:06 – Magic Wand Question: No More Labs?02:04 – Cristian’s Origin Story: From Sorghum to Caltech04:16 – Falling Out of Love with the Wet Lab06:15 – Fixing the Interface Layer in Lab Automation10:00 – Why Scientists & Robots Speak Different Languages13:13 – Hidden Costs: Time, Talent & Trust17:55 – Old Solutions vs New Ideas (Why Parameterization Fails)21:00 – Can LLMs Help? Why They Fall Short Alone23:15 – The Hybrid AI Approach to Translating Science25:00 – Tetsuwan’s Unique UX & Design Philosophy30:07 – The Cloud Lab is Coming… But Are We Ready?35:20 – Why the Last Cloud Labs Didn’t Work (Yet)43:10 – From Algae to Automation: The Founder Mindset49:06 – Teen Court, NASA, and the Systems Lens54:44 – Advice for Young Scientists & Founders57:55 – Why Tetsuwan Supports LabAutomation.io & Lab Auto Wiki1:02:19 – Forest-Minded Thinking: Swag, Collaboration & the Future1:05:26 – Picks of the Week1:09:23 – Wrap Up🔗 Guest & Company Links:🌐 Tetsuwan Scientific: https://www.tetsuwan.com👤 Cristian Ponce on LinkedIn: / cristianponce1 📌 SHORTS (Quick Clips from the Episode) ▶️ • "Magic Wand? No More Labs.” — Cristian Pon... ▶️ • Scientists vs Dead Volume ⚔️ (it’s a fist ... #helicalbrew #aithoughtleaders #HelicalBrew #TetsuwanScientific #LabAutomation #CloudLab #ScientificInnovation #AutomationEngineering #LifeScienceTech #BiotechInnovation #DeadVolume #LLM #SyntheticBiology #BiotechStartups #MolecularAutomation #NextGenLab #BenchToBot #FutureOfScience #TechEntrepreneurs #ScienceMeansBusiness #VeritasiumVibes #LifeScienceInnovation #DrugDiscovery #BiotechAI #MachineLearning #SciencePodcast #AutomationInBiotech #AIInHealthcare #FutureOfScience #HelicalBrew #viralshortsvideo #viralreels #viralvideos #viral_video #labautomation #biotech #biotechstartups #biotechinnovation #biotechnology #science #sciencepodcast #scienceandtech #podcastclips #podcastshorts #ai #aiinscience #aiinbiotech
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    1 時間 11 分