As a physician, scientist, entrepreneur, and biotech CEO, Jeremy Levin has spent his career helping bring innovative medicines to patients. In his book, Biotech in the Balance, he argues that the future of healthcare depends on restoring trust in science, strengthening innovation, and keeping patients at the center of decision-making. In this episode of Get Real, Jeremy joins Jim Weiss to discuss the state of biotechnology, the challenges facing drug development, and why the next generation of medical breakthroughs depends on the choices we make today. This is a conversation about science, leadership, and the future of human health.

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The rules of leadership are changing. According to Bob Pearson, success in the age of AI won't come from replacing human intelligence. It will come from learning how to amplify it. That's the central idea behind his latest book, The Compass. In this episode of Get Real, Bob joins Jim Weiss to explore how leaders can navigate a world being reshaped by artificial intelligence, why curiosity matters more than ever, and how organizations can adapt without losing their humanity. This is a conversation about leadership, innovation, and finding direction during times of rapid change.

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From helping build one of the world's leading oncology businesses to serving as CEO of a Fortune 500 company, Frank Clyburn has spent his career at the intersection of healthcare, leadership, and innovation. His work helped shape the commercialization of breakthrough medicines, including advances that transformed cancer care. In this episode of Get Real, Frank joins Jim Weiss to discuss the lessons that shaped him, the importance of putting patients first, and how leaders can balance innovation, access, and business success. This is a conversation about resilience, opportunity, and creating lasting impact.

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For more than two decades, Dr. Richard Pazdur helped shape the future of cancer treatment from inside the FDA, overseeing many of the therapies that transformed care for patients around the world. He played a central role in building the FDA's oncology review programs and accelerating access to groundbreaking medicines. In this episode of Get Real, Dr. Pazdur joins Jim Weiss to discuss the evolution of cancer care, the challenge of balancing speed with safety, and what it takes to bring lifesaving treatments from the lab to patients. They also explore the future of oncology, global innovation, and why there is still reason for optimism in the fight against cancer.

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Robin Carhart-Harris is one of the world's leading researchers studying psychedelics, consciousness, and mental health. For decades, psychedelics sat on the fringes of medicine. Today, they're at the center of some of the most promising research into depression, well-being, and the human mind. Robin's groundbreaking work has helped uncover how substances like psilocybin and LSD affect the brain and their potential role in treating mental illness. Robin joins Jim to explore the science behind psychedelics, what brain imaging studies reveal about consciousness, and why researchers are rethinking the treatment of depression and other mental health conditions. They discuss the role of set and setting, the differences between clinical and non-clinical use, and what the future may hold for psychedelic medicine.

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Robert Croak never set out to create one of the biggest product crazes of the 21st century. But when he spotted an unusual silicone rubber band at a trade show, he saw something others didn't. That insight became Silly Bandz, a global phenomenon that transformed a simple idea into a massive business. In this episode of Get Real, Robert joins Jim Weiss to share the entrepreneurial journey behind his success, from a challenging upbringing and early business ventures to building iconic brands, investing in startups, and teaching financial literacy. This is a conversation about spotting opportunity, trusting your instincts, and the persistence required to turn a simple idea into something extraordinary.

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When Monica Coenraads’ daughter was diagnosed with Rett syndrome, she refused to accept that nothing could be done. As founder and CEO of the Rett Syndrome Research Trust, she has helped advance groundbreaking research aimed at treating the disorder at its genetic root. In this episode of Get Real, Monica joins Jim Weiss to discuss the personal journey that led her into rare disease advocacy, the promise of gene therapy, and what it takes to turn urgency, hope, and determination into scientific progress. This is a conversation about resilience, purpose, and the power of one family’s fight to change the future for thousands of others.

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Jim gets real about death with someone who's embracing that conversation. Tamatha Thomas-Haase, host of the podcast Grand Exit, has been living with metastatic breast cancer since 2018. While most of us avoid talking about mortality, Tamatha has made it her mission to confront it head-on and help others do the same. Jim and Tamatha explore what it means to live with uncertainty, redefine hope, and find joy in the time we have. They discuss caregiving, advocacy, and the unexpected lessons that come from facing life's inevitable realities. Tamatha believes that talking about death helps us live more fully. And by the end of this episode, we're sure you'll agree.

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