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Today I’m sharing my conversation with Dr. David Nutt—Edmond J. Safra Professor of Neuropsychopharmacology at Imperial College London—one of the most influential and outspoken figures in modern psychiatric research and drug policy. It’s a wide-ranging chat about addiction science, pharmacology, and the past and future of medication development—including his current focus on psychedelics.

In particular, we turn to the intellectual foundations of addiction science and focus on one of Dave’s core arguments: the field went down the wrong path by treating dopamine as a master explanation for addiction.

Check out my Substack post for more about Dr. Nutt's work

Find him on YouTube, Instagram, Bluesky, Twitter/X, and at the charity he founded, DrugScience.org.uk.

Sign up for my newsletter and immediately receive my own free guide to the many pathways to recovery, as well as regular updates on new interviews, material, and other writings.

Sign up for my newsletter and immediately receive my free guide to the many pathways to recovery, as well as regular updates on new interviews, material, and other writings.

This is a special audio edition of my recent Substack conversation with neuroscientist and writer Tim Requarth. The full post—including the video and more detailed show notes—is available on my Substack.

Neuroscientist, writer, and NYU faculty member Tim Requarth joins me to talk about what "AI dependency" really means. Some behavioral addiction researchers are proposing that "ChatGPT addiction" qualifies as a bonafide mental disorder, while others strongly object! We explore how tools like ChatGPT affect our thinking and attention, and whether AI can actually cause "brain damage"--as recent headlines have claimed. We discuss what happens when people lose trust in their own thinking, why productive struggle matters, and why AI can’t challenge your assumptions the way a real friend would.

Check out my Substack post for more!

Sign up for my newsletter and immediately receive my own free guide to the many pathways to recovery, as well as regular updates on new interviews, material, and other writings.

Sign up for my newsletter and immediately receive my free guide to the many pathways to recovery, as well as regular updates on new interviews, material, and other writings.

Today I’m excited to share my conversation with Melody Glenn, an emergency medicine doc, addiction physician, and Associate Professor at University of Arizona, who just published her first book: Mother of Methadone: A Doctor's Quest, a Forgotten History, and a Modern-Day Crisis. It’s an important story that reveals how we got into our current mess of a treatment system and challenges some foundational myths about addiction that are deeply ingrained in our cultural history. Ultimately, it’s an inspiring biography of a pioneer who was able totally transform care, even during troubled times.

Check out my Substack post for more about Melody's work!

Sign up for my newsletter and immediately receive my own free guide to the many pathways to recovery, as well as regular updates on new interviews, material, and other writings.