『Episode 13: N-Acetylcysteine —Rebuilding your body’s antioxidant defense system』のカバーアート

Episode 13: N-Acetylcysteine —Rebuilding your body’s antioxidant defense system

Episode 13: N-Acetylcysteine —Rebuilding your body’s antioxidant defense system

無料で聴く

ポッドキャストの詳細を見る

In this episode of Molecules Matter with Dr. Dan, we break down N-acetylcysteine (NAC)—a powerful molecule that helps your body produce glutathione, often called the “master antioxidant.”


Unlike typical supplements that act directly, NAC works upstream by giving your body the building blocks it needs to protect itself from oxidative stress, inflammation, and cellular damage.


We explore how NAC functions at the molecular level, including its role in redox balance, neurotransmitter regulation, and mitochondrial protection. We also dive into the scientific literature behind its effects on brain health, addiction pathways, fertility, kidney protection, and more.


You’ll learn:

• What NAC is and how it’s made

• Why glutathione is critical for health

• How NAC supports brain function and recovery

• Its role in addiction, fertility, and metabolic health

• Where the research is strong—and where it’s limited

• Evidence-based dosing and safety considerations


NAC has been studied in conditions like traumatic brain injury, Parkinson’s disease, schizophrenia, PCOS, male infertility, and acute kidney injury. It is also used clinically to prevent liver damage in cases of toxicity.


Typical dose: 600 mg twice daily


As always, consult your healthcare provider before starting any new supplement, especially if you have a medical condition or take medications.


If you enjoyed this episode, follow the podcast, share it with someone who would benefit, and explore more at www.drdangubler.com


Because at the end of the day—molecules matter.



References (PubMed):


Monti DA et al. (2025). J Head Trauma Rehabil. doi:10.1097/HTR.0000000000000976

Logge WB et al. (2025). Psychopharmacology. doi:10.1007/s00213-024-06656-z

Heidari B et al. (2023). Rev Recent Clin Trials. doi:10.2174/0115748871250545230919055109

Shahreki E et al. (2022). Pharmacology. doi:10.1159/000525094

Javaherforooshzadeh F et al. (2021). J Cardiothorac Surg. doi:10.1186/s13019-021-01550-7

Mullier E et al. (2019). Int J Neuropsychopharmacol. doi:10.1093/ijnp/pyz022

Monti DA et al. (2019). Clin Pharmacol Ther. doi:10.1002/cpt.1548

Christensen PM, Bangsbo J. (2019). Eur J Appl Physiol. doi:10.1007/s00421-019-04132-7

Jannatifar R et al. (2019). Reprod Biol Endocrinol. doi:10.1186/s12958-019-0468-9

Hashemi G et al. (2019). Curr Rheumatol Rev. doi:10.2174/1573403X14666180926100811

Sepehrmanesh Z et al. (2018). Prog Neuropsychopharmacol Biol Psychiatry. doi:10.1016/j.pnpbp.2017.11.001

Dean OM et al. (2017). Aust N Z J Psychiatry. doi:10.1177/0004867416652735

Javanmanesh F et al. (2016). Gynecol Endocrinol. doi:10.3109/09513590.2015.1115974

Doosti A et al. (2014). Noise Health. doi:10.4103/1463-1741.137057

Ozaydin M et al. (2014). Clin Cardiol. doi:10.1002/clc.22227

Hoffer ME et al. (2013). PLoS One. doi:10.1371/journal.pone.0054163

Berk M et al. (2012). BMC Med. doi:10.1186/1741-7015-10-91

Grant JE et al. (2007). Biol Psychiatry. doi:10.1016/j.biopsych.2006.11.021

adbl_web_anon_alc_button_suppression_c
まだレビューはありません