Everyone's talking about Ozempic, Wegovy, and Mounjaro. But nobody's talking about what's actually happening to your body when you use them — and what happens when you stop.

The research is clear: without lifting and eating enough protein, up to 25-40% of weight lost on these drugs is muscle. Not fat. Muscle. And when people stop? Most of the weight comes back — fast.

In this episode, we break down what the science actually says about GLP-1 medications and body composition, why muscle is your most important long-term asset, and what every woman needs to be doing — whether she's on a weight loss drug or not.

You'll learn:

• Why muscle loss is the hidden cost of GLP-1 drugs — and how to prevent it
• What a real-world case series found when patients combined resistance training + high protein with their medication (the results are wild)
• Why weight always comes back when you stop — and what actually protects you
• How much protein you actually need and how to hit it without going over calories
• Why lifting heavy is the most important thing any woman can do for her long-term health

Whether you're on these medications, considering them, or just watching everyone around you talk about them — this episode is essential listening. 💚

References:

doi:10.1177/2050313X251388724

doi:10.1016/S2589-5370(25)00614-5.

doi:10.1001/jamainternmed.2025.6112

doi:10.1001/jama.2023.24945

doi:10.1016/S2213-8587(24)00182-7

Love this episode? 💚 Share it on your intagram story and tag me @sami_livestrong

Want to connect?

🤝🏽 Follow me on Instagram:

https://www.instagram.com/sami_livestrong/

💪🏼 Ready to start living a Stronger Life — inside and out?
Apply for my online coaching program here:

bit.ly/ApplywithSami

🔥 Please subscribe, rate & review if you enjoyed this ep!

Disclaimer: The Live Stronger with Sami podcast is not a substitute for a health professional's individualised advice. The advice given is general in nature and should not be used to treat any medical conditions, illnesses or injuries. Please consult your medical professional before implementing any of the advice discussed in this episode.