Ep. 266: “From Stem Cells to Cortical Circuits” Featuring Dr. Pierre Vanderhaeghen
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Dr. Pierre Vanderhaeghen is a Professor and Principal Investigator at VIB-KU Leuven Center for Brain & Disease Research. His lab studies the mechanisms of cortical development and brain evolution. He talks about species-specific neuronal development, human neuron excitability, and playing in a rock cover band!
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Modeling Cancer Ex Vivo – Induced mini-colons recapitulated hallmarks of colorectal tumors.
Human Embryo Gastrulation – Scientists reconstructed a 3D model of a gastrulating human embryo using spatial transcriptomics.
Treating Timothy Syndrome – Antisense oligonucleotides rescued defects in patient-derived cortical organoids.
Sympathetic Neurons in Jawless Vertebrates – Scientists identified trunk sympathetic neurons in the sea lamprey.
Image courtesy of Dr. Pierre Vanderhaeghen
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