In this episode, Roy Richardson and Sean Murphy sit down with trailblazing founder and CEO Shari Costantini—a woman who has built not one, but two industry-shaping companies.

Shari first scaled Avant Healthcare Professionals into one of the largest international healthcare staffing firms in the U.S., earning national recognition, including EY Entrepreneur of the Year and Orlando Business Journal CEO of the Year. Today, she’s disrupting an entirely different arena as co-founder and CEO of Kismet Technologies, the company behind a first-of-its-kind mineral-based antimicrobial technology poised to reshape everything from hospital safety to food packaging sustainability.

Shari opens up about:

• The unexpected path from clinical nursing to building a category-defining staffing enterprise.
• What truly differentiated Avant and how a focus on cultural and clinical prep created unmatched loyalty.
• How Kismet’s breakthrough tech works—and why its regenerative antimicrobial properties are a game-changing answer to rising resistance, food spoilage, and regulatory shifts.
• Weathering a founder departure, filling a steep technical knowledge gap, and leading through the toughest 90 days of her career.
• Her philosophy on leadership, humility, lifelong learning, and building teams that think big.
• What it really takes to earn investor trust, including raising over $58M across venture capital, PE, and strategic partners.
• Her long-term vision: a safer, greener, healthier world powered by sustainable materials science.

Along the way, Shari shares personal stories—from her daughter’s successful battle with pediatric cancer to her evolution as a leader who adapts to every personality in the room without compromising on integrity.

Whether you’re a founder, operator, investor, or simply someone navigating big leadership moments, this conversation is packed with wisdom, resilience, and inspiration.

This episode is a masterclass in reinvention, grit, and building with purpose.

Connect with the Dynamic Business Leaders Podcast Hosts:

• LinkedIn: Roy Richardson
• LinkedIn: Sean Murphy

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